ID B1I5J7_DESAP Unreviewed; 692 AA.
AC B1I5J7;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN OrderedLocusNames=Daud_1748 {ECO:0000313|EMBL:ACA60244.1};
OS Desulforudis audaxviator (strain MP104C).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforudis.
OX NCBI_TaxID=477974 {ECO:0000313|EMBL:ACA60244.1, ECO:0000313|Proteomes:UP000008544};
RN [1] {ECO:0000313|Proteomes:UP000008544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP104C {ECO:0000313|Proteomes:UP000008544};
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Bruce D., Pitluck S., Lowry S.R., Larimer F., Land M.L.,
RA Hauser L., Kyrpides N., Ivanova N.N., Richardson P.;
RT "Complete sequence of chromosome of Desulforudis audaxviator MP104C.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACA60244.1, ECO:0000313|Proteomes:UP000008544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP104C {ECO:0000313|EMBL:ACA60244.1,
RC ECO:0000313|Proteomes:UP000008544};
RX PubMed=18845759; DOI=10.1126/science.1155495;
RA Chivian D., Brodie E.L., Alm E.J., Culley D.E., Dehal P.S., Desantis T.Z.,
RA Gihring T.M., Lapidus A., Lin L.H., Lowry S.R., Moser D.P.,
RA Richardson P.M., Southam G., Wanger G., Pratt L.M., Andersen G.L.,
RA Hazen T.C., Brockman F.J., Arkin A.P., Onstott T.C.;
RT "Environmental genomics reveals a single-species ecosystem deep within
RT Earth.";
RL Science 322:275-278(2008).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP000860; ACA60244.1; -; Genomic_DNA.
DR AlphaFoldDB; B1I5J7; -.
DR STRING; 477974.Daud_1748; -.
DR KEGG; dau:Daud_1748; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_9; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000008544; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:ACA60244.1};
KW Cilium {ECO:0000313|EMBL:ACA60244.1};
KW Flagellum {ECO:0000313|EMBL:ACA60244.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000008544};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 18..36
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 42..61
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 113..132
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 242..264
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 692 AA; 75664 MW; DB2EFB0344D28CDC CRC64;
MEVAVVERQS WIKRYADMVI AGLIIGIVLL IIIPLPPAAL DFFLVISLGL GMIILLITLF
VTDALEFSVF PTLLLVVTLY RLALNISSTR LILGEAEAGK VIAAFGEFVV GGSYIVGFIV
FLIITLVQFV VITNGSSRVA EVAARFTLDA MPGKQMAIDS DFNAGLITEQ EARERRRRLQ
RESDFYGAMD GATKFVRGDA IAGLVIVFIN IIGGLVIGIA VMQMDAQQAL TTFTILTIGD
GLVTQIPAVL VSTATGILVT RAASDTSFGG DVSRQFLSFP RVLVVAAGVL VVMGLIPAMP
NLLFLGMGAA LGLLAYNLNR EERRREVAAA EQAAAREVRE QKREPENVLT YFQVDPLEVE
IGYNLIPLAS EEQGGDLLHR VAGVRRQCAQ ELGIYVRPIR IRDNLQLKPN TYVFKMRGVE
AAEGELEPGR YLAMDPTGDR TLQGIPTREP TFGLPAWWIA PENREAAEID GFTVVDPATV
LATHLSEFIK RHGHELLGRQ EVQELLNVVK EKNPAVVEEL VPGLLSLGEV QKVLQNLLKE
RVPIRDMVSI LEALADCARQ DRNEDALTEA ARKALSRTIS RLHAREGGKI RVITLHPRLE
QRLIDAVQPT ALGAFPVLEP GTAQRVIQSL GAAVEKAQSK GHLPAVLCSS RVRLPFRRLT
ERHFPHLSIL ALQEIAPQID VEAVGTVTLD ED
//
