ID B1IMH2_CLOBK Unreviewed; 111 AA.
AC B1IMH2;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE RecName: Full=Anti-sigma F factor antagonist {ECO:0000256|ARBA:ARBA00020784, ECO:0000256|RuleBase:RU003749};
DE AltName: Full=Stage II sporulation protein {ECO:0000256|RuleBase:RU003749};
GN Name=spoIIAA {ECO:0000313|EMBL:ACA45291.1};
GN OrderedLocusNames=CLD_1451 {ECO:0000313|EMBL:ACA45291.1};
OS Clostridium botulinum (strain Okra / Type B1).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=498213 {ECO:0000313|EMBL:ACA45291.1, ECO:0000313|Proteomes:UP000008541};
RN [1] {ECO:0000313|EMBL:ACA45291.1, ECO:0000313|Proteomes:UP000008541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Okra / Type B1 {ECO:0000313|Proteomes:UP000008541};
RX PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT plasmids.";
RL PLoS ONE 2:E1271-E1271(2007).
CC -!- FUNCTION: In the phosphorylated form it could act as an anti-anti-sigma
CC factor that counteracts SpoIIAB and thus releases sigma f from
CC inhibition. {ECO:0000256|ARBA:ARBA00001976}.
CC -!- SIMILARITY: Belongs to the anti-sigma-factor antagonist family.
CC {ECO:0000256|ARBA:ARBA00009013, ECO:0000256|RuleBase:RU003749}.
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DR EMBL; CP000939; ACA45291.1; -; Genomic_DNA.
DR RefSeq; WP_003357811.1; NC_010516.1.
DR AlphaFoldDB; B1IMH2; -.
DR GeneID; 5187346; -.
DR KEGG; cbb:CLD_1451; -.
DR HOGENOM; CLU_115403_7_0_9; -.
DR Proteomes; UP000008541; Chromosome.
DR GO; GO:0043856; F:anti-sigma factor antagonist activity; IEA:InterPro.
DR GO; GO:0045152; F:antisigma factor binding; IEA:InterPro.
DR GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR CDD; cd07043; STAS_anti-anti-sigma_factors; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR003658; Anti-sigma_ant.
DR InterPro; IPR014237; Anti-sigma_F_ant.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00377; ant_ant_sig; 1.
DR NCBIfam; TIGR02886; spore_II_AA; 1.
DR PANTHER; PTHR33495; ANTI-SIGMA FACTOR ANTAGONIST TM_1081-RELATED-RELATED; 1.
DR PANTHER; PTHR33495:SF2; ANTI-SIGMA-B FACTOR ANTAGONIST; 1.
DR Pfam; PF01740; STAS; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Sporulation {ECO:0000256|ARBA:ARBA00022969}.
FT DOMAIN 1..111
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 111 AA; 12695 MW; E972896BFC21BFA2 CRC64;
MYLKFDKKAD KLIVTMAGEL DHHSAEEVRN VIDDRLDREN LNKLILDFSK VNFMDSSGIG
VVIGRYKKLS LRDGKVCLTN VQEAVRRVFE LSGMFKIVNL YDSVDEAVEN L
//