ID NORR_ECOLC Reviewed; 504 AA.
AC B1IUX0;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 01-MAY-2013, entry version 42.
DE RecName: Full=Anaerobic nitric oxide reductase transcription regulator NorR;
GN Name=norR; OrderedLocusNames=EcolC_1003;
OS Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=481805;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8739 / DSM 1576 / Crooks;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E.,
RA Tice H., Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T.,
RA Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Ingram L., Richardson P.;
RT "Complete sequence of Escherichia coli C str. ATCC 8739.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the expression of anaerobic nitric oxide
CC (NO) reductase, acts as a transcriptional activator for at least
CC the norVW operon. Activation also requires sigma-54 (By
CC similarity).
CC -!- PATHWAY: Nitrogen metabolism; nitric oxide reduction.
CC -!- SIMILARITY: Contains 1 sigma-54 factor interaction domain.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; CP000946; ACA76672.1; -; Genomic_DNA.
DR RefSeq; YP_001723999.1; NC_010468.1.
DR ProteinModelPortal; B1IUX0; -.
DR SMR; B1IUX0; 185-431, 455-503.
DR STRING; 481805.EcolC_1003; -.
DR EnsemblBacteria; ACA76672; ACA76672; EcolC_1003.
DR GeneID; 6067653; -.
DR KEGG; ecl:EcolC_1003; -.
DR PATRIC; 18224637; VBIEscCol82905_1070.
DR eggNOG; COG3604; -.
DR HOGENOM; HOG000058487; -.
DR KO; K12266; -.
DR OMA; DSEAKMS; -.
DR ProtClustDB; PRK05022; -.
DR BioCyc; ECOL481805:GI3G-1024-MONOMER; -.
DR UniPathway; UPA00638; -.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:HAMAP.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:HAMAP.
DR GO; GO:0007600; P:sensory perception; IEA:HAMAP.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.60; -; 1.
DR HAMAP; MF_01314; NorR; 1; -.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR009057; Homeodomain-like.
DR InterPro; IPR023944; NorR.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00065; GAF; 1.
DR SUPFAM; SSF46689; Homeodomain_like; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; DNA-binding; Nucleotide-binding;
KW Phosphoprotein; Transcription; Transcription regulation.
FT CHAIN 1 504 Anaerobic nitric oxide reductase
FT transcription regulator NorR.
FT /FTId=PRO_1000086223.
FT DOMAIN 187 416 Sigma-54 factor interaction.
FT NP_BIND 215 222 ATP (Potential).
FT NP_BIND 278 287 ATP (Potential).
FT DNA_BIND 479 498 H-T-H motif (By similarity).
FT MOD_RES 57 57 4-aspartylphosphate (By similarity).
SQ SEQUENCE 504 AA; 55305 MW; DD50E722F1CB22A9 CRC64;
MSFSVDVLAN IAIELQRGIG HQDRFQRLIT TLRQVLECDA SALLRYDSRQ FIPLAIDGLA
KDVLGRRFAL EGHPRLEAIA RAGDVVRFPA DSELPDPYDG LIPGQESLKV HACVGLPLFA
GQNLIGALTL DGMQPDQFDV FSDEELRLIA ALAAGALSNA LLIEQLESQN MMPGDATPFE
AVKQTQMIGL SPGMTQLKKE IEIVAASDLN VLISGETGTG KELVAKAIHE ASPRAVNPLV
YLNCAALPES VAESELFGHV KGAFTGAISN RSGKFEMADN GTLFLDEIGE LSLALQAKLL
RVLQYGDIQR VGDDRSLRVD VRVLAATNRD LREEVLAGRF RADLFHRLSV FPLSVPPLRE
RGDDVILLAG YFCEQCRLRL GLSRVVLSAG ARNLLQHYRF PGNVRELEHA IHRAVVLARA
TRNGDEVILE AQHFAFPEVT LPPPEAAAVP VVKQNLREAT EAFQRETIRQ ALAQNHHNWA
ACARMLETDV ANLHRLAKRL GMKD
//
