ID B1L6L9_KORCO Unreviewed; 703 AA.
AC B1L6L9;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN OrderedLocusNames=Kcr_1352 {ECO:0000313|EMBL:ACB08098.1};
OS Korarchaeum cryptofilum (strain OPF8).
OC Archaea; Candidatus Korarchaeota; Korarchaeum.
OX NCBI_TaxID=374847 {ECO:0000313|EMBL:ACB08098.1, ECO:0000313|Proteomes:UP000001686};
RN [1] {ECO:0000313|EMBL:ACB08098.1, ECO:0000313|Proteomes:UP000001686}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OPF8 {ECO:0000313|Proteomes:UP000001686};
RX PubMed=18535141; DOI=10.1073/pnas.0801980105;
RA Elkins J.G., Podar M., Graham D.E., Makarova K.S., Wolf Y., Randau L.,
RA Hedlund B.P., Brochier-Armanet C., Kunin V., Anderson I., Lapidus A.,
RA Goltsman E., Barry K., Koonin E.V., Hugenholtz P., Kyrpides N., Wanner G.,
RA Richardson P., Keller M., Stetter K.O.;
RT "A korarchaeal genome reveals new insights into the evolution of the
RT Archaea.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:8102-8107(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
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DR EMBL; CP000968; ACB08098.1; -; Genomic_DNA.
DR AlphaFoldDB; B1L6L9; -.
DR STRING; 374847.Kcr_1352; -.
DR EnsemblBacteria; ACB08098; ACB08098; Kcr_1352.
DR KEGG; kcr:Kcr_1352; -.
DR eggNOG; arCOG00439; Archaea.
DR HOGENOM; CLU_000995_6_0_2; -.
DR InParanoid; B1L6L9; -.
DR PhylomeDB; B1L6L9; -.
DR Proteomes; UP000001686; Chromosome.
DR GO; GO:0042555; C:MCM complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR018525; MCM_CS.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00847; MCM_1; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000001686}.
FT DOMAIN 294..500
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 703 AA; 79373 MW; 0A3BCACED3E0CF73 CRC64;
MVEKSPLMSS EELVEKYKSF IRYYRDENNE PIYQKALAQL IEEQRRSLSV NWYHLYNFNP
DFREIAEDIV MNPSLHISAG SSAIKELVME LMPMTEEFRI YSEGDFHLRF YNVPTKASFR
DLTKFSIGRL IEIEGIITRV SDIYDKLVRA SFICTNCGRI EEIDIIGEKL RVLEKCPECG
APMKLDHEMS KFIRWRSVRI QERPEDLPPG MMPEHVDGIL TDDIVDDVKP GDRVRVTGII
RIKPARRDEG REGLIYKRYL EIIHVEVPNR VYEKLEITPE DEEEILKLSE REDLEELIVK
SIAPSVFGWA DVKRAIAYAL FGGSTKILAD GSKVRGEINV LLVGDPGVAK SQLLKYTAQL
APRGLYTTGK GSTAAGLTAA VVRDSATGGW TLEAGALVLA DMGVACIDEF DKMSEDDRRS
IHEAMEQQTI SIAKAGIVAT LNARTTIIAA ANPKKGKYDD YVTVAENINL PPTILSRFDL
VFIMKDRPGV ESDSMVAEHI LITRMGRNPE AKPPIDPNLL KKYIAYAKQN IDPILTDEAA
ERIKNYYVDV RGRGIKESEE GIVQDLISIT PRQLEALIRL SEARARMHLR REVTAEDAEM
AINLMEITLK GAAYDIVSGH FDITGWMTGI SFPEVKRREV VFQIIKQLAE GSEDGLVDRD
VVVRMAAERL NLKGKEYVIE DILRKLNEDG LIIFPPGGKI RLI
//
