ID B1LVJ9_METRJ Unreviewed; 345 AA.
AC B1LVJ9;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=Response regulator receiver modulated metal dependent phosphohydrolase {ECO:0000313|EMBL:ACB24080.1};
GN OrderedLocusNames=Mrad2831_2085 {ECO:0000313|EMBL:ACB24080.1};
OS Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 /
OS NBRC 15690 / NCIMB 10815 / 0-1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=426355 {ECO:0000313|EMBL:ACB24080.1, ECO:0000313|Proteomes:UP000006589};
RN [1] {ECO:0000313|EMBL:ACB24080.1, ECO:0000313|Proteomes:UP000006589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 /
RC 0-1 {ECO:0000313|Proteomes:UP000006589};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Marx C.J., Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium radiotolerans JCM
RT 2831.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001001; ACB24080.1; -; Genomic_DNA.
DR RefSeq; WP_012319060.1; NC_010505.1.
DR AlphaFoldDB; B1LVJ9; -.
DR STRING; 426355.Mrad2831_2085; -.
DR KEGG; mrd:Mrad2831_2085; -.
DR PATRIC; fig|426355.14.peg.2142; -.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_000445_92_10_5; -.
DR OrthoDB; 9802066at2; -.
DR Proteomes; UP000006589; Chromosome.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:UniProt.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ACB24080.1};
KW Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}.
FT DOMAIN 2..121
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 148..345
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 170..294
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT MOD_RES 54
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 345 AA; 37658 MW; A1F152DADDD3118D CRC64;
MLALILDDSE MNNLLIMQAL KPVADCEPVA FTCPVTALDF LRAHVDRIGV VVTDYDMPGL
TGLEVIAAAR AIPGFAHVPI VMVTSLDQRS LRHEALRAGA TDFLGKPCDP VEIQARITNL
MKISAAHRQE QDRAAWLARE VAAAVAVIEA REREIIALLM RAAEHRDTDT GDHIARVAGY
VGVIARNLGF NPEEIRILKL ASTMHDVGKI GVPDAILLKP GPLSAEERAE MEKHAERGRR
ILEGSTSDVV RLAAEIAESH HERWDGTGYP KGLRGEAIPL SGRIVAVADV FDALVTERPY
KAAWPLERAR AFVADQSGRH FDPRCVEAFL AGWEAVTRTC LRAAA
//
