ID B1M265_METRJ Unreviewed; 424 AA.
AC B1M265;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACB24676.1};
GN OrderedLocusNames=Mrad2831_2692 {ECO:0000313|EMBL:ACB24676.1};
OS Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 /
OS NBRC 15690 / NCIMB 10815 / 0-1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=426355 {ECO:0000313|EMBL:ACB24676.1, ECO:0000313|Proteomes:UP000006589};
RN [1] {ECO:0000313|EMBL:ACB24676.1, ECO:0000313|Proteomes:UP000006589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 /
RC 0-1 {ECO:0000313|Proteomes:UP000006589};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Marx C.J., Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium radiotolerans JCM
RT 2831.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001001; ACB24676.1; -; Genomic_DNA.
DR RefSeq; WP_012319645.1; NC_010505.1.
DR AlphaFoldDB; B1M265; -.
DR STRING; 426355.Mrad2831_2692; -.
DR KEGG; mrd:Mrad2831_2692; -.
DR PATRIC; fig|426355.14.peg.2757; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_1_4_5; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000006589; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR PANTHER; PTHR30469:SF37; RAGD PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 82..328
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 397..424
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 116..157
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 424 AA; 45006 MW; 4C964625DD9226B8 CRC64;
MKAHDAGADV PPPPGKAPFL LVSLAGLGLL AWGAYGHWQR DAAATATLER IKTLVPQVRT
VAVERAEGPL DLVLPGEMQA FTTAAIAARA TGYVAERRVD IGSRVKAGDL LLRIAAPDLD
QQLAQAEAQV GQLKAQLLQA RAQVEQARAN VNLANLTNNR TSTLAVQGWA SRQNADNTQA
GVLSQAAALA AAEAGVKVAT ANIKAQEAVV DRLKALTAFE RVVAPFDGVV TVRNVDVGDL
VRADNGGTPL LSMDQDSLLR ITVNVPQKDA VGVEPGVRAE ITVPQMPGRR FDGFVERSSV
ALNAASRTLT TQVDVPNADR ALRAGLYAYV TLKIPRAEPG VTIPAEATVF SGNDLRVATL
TDDDRVTWRT IRVRRDLGRT LELESGLPAE TRIIYSPAPD LRDGQSVEPL KPSPAPGPLR
SAQR
//
