ID B1M9F4_METRJ Unreviewed; 463 AA.
AC B1M9F4;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Xanthine permease {ECO:0000313|EMBL:ACB28129.1};
GN OrderedLocusNames=Mrad2831_6205 {ECO:0000313|EMBL:ACB28129.1};
OS Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 /
OS NBRC 15690 / NCIMB 10815 / 0-1).
OG Plasmid pMRAD01 {ECO:0000313|EMBL:ACB28129.1,
OG ECO:0000313|Proteomes:UP000006589}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=426355 {ECO:0000313|EMBL:ACB28129.1, ECO:0000313|Proteomes:UP000006589};
RN [1] {ECO:0000313|EMBL:ACB28129.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 2831 {ECO:0000313|EMBL:ACB28129.1};
RC PLASMID=pMRAD01 {ECO:0000313|EMBL:ACB28129.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Marx C.J., Richardson P.;
RT "Complete sequence of plasmid1 of Methylobacterium radiotolerans JCM
RT 2831.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001002; ACB28129.1; -; Genomic_DNA.
DR RefSeq; WP_012329915.1; NC_010510.1.
DR AlphaFoldDB; B1M9F4; -.
DR KEGG; mrd:Mrad2831_6205; -.
DR PATRIC; fig|426355.14.peg.6281; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_8_2_5; -.
DR OrthoDB; 9805749at2; -.
DR Proteomes; UP000006589; Plasmid pMRAD01.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:ACB28129.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 463 AA; 47517 MW; BFDD1E34362542C5 CRC64;
MTSHDRTTRE VDAVDAIPPL PKLLAYGMQH VLVMSAGAVA PPLILGAAMN LPTETVAYLI
NCDLLVTGIA ILIQSLGLGI FGIRLPVIMG VSFAAVGPMV AMAQDPTIGL PGIFGATIGA
GVFGLLLRPF FSKLASFFPP LVTGTVILII GVTLLPVGIN WAGGGFGAAD FGAPVHLGVA
AFVLAVILVV SRFATGFVAN VAVLIGLVAG LCLAWPLGLF RLDGLAERPL IALVTPFHFG
WPTFHLTAVA AMCIVMMVTL VESTGMFLAV GDIVGRPVDK RTLTRGLMAD SLSTLIAGCL
NTFPHTSFSQ NVGLVNMTRV RSRYVTVAAG FIILGVSLLP KVAFAVASIP PAVLGGAGIV
IFGMVAAAGL KIVSGADLGD RRNQIVVAVS IGLSLIPMAA PKLFAATAPD WAGPILHSGI
TLGAIGAIVL NLLLNSDRLG AGAEHRAADA EPDFAHAAVL DRA
//
