ID B1MIV7_MYCA9 Unreviewed; 235 AA.
AC B1MIV7;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=VTT domain-containing protein {ECO:0000259|Pfam:PF09335};
GN OrderedLocusNames=MAB_4255 {ECO:0000313|EMBL:CAM64328.1};
OS Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CCUG 20993 / CIP
OS 104536 / JCM 13569 / NCTC 13031 / TMC 1543 / L948) (Mycobacterium
OS abscessus).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacteroides; Mycobacteroides abscessus.
OX NCBI_TaxID=561007 {ECO:0000313|EMBL:CAM64328.1, ECO:0000313|Proteomes:UP000007137};
RN [1] {ECO:0000313|EMBL:CAM64328.1, ECO:0000313|Proteomes:UP000007137}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 /
RC TMC 1543 {ECO:0000313|Proteomes:UP000007137};
RX PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA Gaillard J.L.;
RT "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT Mycobacterium abscessus.";
RL PLoS ONE 4:E5660-E5660(2009).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU367016};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU367016}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DedA family. {ECO:0000256|ARBA:ARBA00010792,
CC ECO:0000256|RuleBase:RU367016}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU458896; CAM64328.1; -; Genomic_DNA.
DR RefSeq; WP_005062515.1; NZ_MLCG01000001.1.
DR AlphaFoldDB; B1MIV7; -.
DR GeneID; 66969690; -.
DR KEGG; mab:MAB_4255; -.
DR Proteomes; UP000007137; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032818; DedA.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR30353; INNER MEMBRANE PROTEIN DEDA-RELATED; 1.
DR PANTHER; PTHR30353:SF0; TRANSMEMBRANE PROTEIN; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU367016};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367016};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU367016};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU367016}.
FT TRANSMEM 27..46
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 53..70
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 165..186
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 192..214
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT DOMAIN 50..185
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
SQ SEQUENCE 235 AA; 25167 MW; C4267B2322BC928A CRC64;
MILASSTTTL ALMPSFLDPV KLLGQFGTLA LLGLLVVIFV ESGVLFPVLP GDSLLFVAGM
LAAGSAAAAA AEGAPQANFQ LWQLLVFIPI AAILGGQVGY WIGRGIGTSM FKPDARFLKQ
RYLDEAHAFF EKRGPFAIVI ARFVPIVRTL APITAGAARM SYPIFALYNI VGAVVWGVGI
TLLGYWLGQF PIIQKLLEPI FILIVLASVA PMFLEWMRRR KAGKTAEGSE TPTGA
//
