ID B1NI95_ERISI Unreviewed; 679 AA.
AC B1NI95;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Prophenoloxdiase {ECO:0000313|EMBL:ABS19633.1};
GN Name=proPO {ECO:0000313|EMBL:ABS19633.1};
OS Eriocheir sinensis (Chinese mitten crab).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;
OC Eubrachyura; Grapsoidea; Varunidae; Eriocheir.
OX NCBI_TaxID=95602 {ECO:0000313|EMBL:ABS19633.1};
RN [1] {ECO:0000313|EMBL:ABS19633.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18160310; DOI=10.1016/j.fsi.2007.08.006;
RA Gai Y., Zhao J., Song L., Li C., Zheng P., Qiu L., Ni D.;
RT "A prophenoloxidase from the Chinese mitten crab Eriocheir sinensis: gene
RT cloning, expression and activity analysis.";
RL Fish Shellfish Immunol. 24:156-167(2008).
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DR EMBL; EF493829; ABS19633.1; -; mRNA.
DR AlphaFoldDB; B1NI95; -.
DR SMR; B1NI95; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR Gene3D; 2.60.40.1520; Hemocyanin, C-terminal domain; 1.
DR Gene3D; 1.20.1370.10; Hemocyanin, N-terminal domain; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR013788; Hemocyanin/hexamerin.
DR InterPro; IPR000896; Hemocyanin/hexamerin_mid_dom.
DR InterPro; IPR005203; Hemocyanin_C.
DR InterPro; IPR037020; Hemocyanin_C_sf.
DR InterPro; IPR005204; Hemocyanin_N.
DR InterPro; IPR036697; Hemocyanin_N_sf.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11511; LARVAL STORAGE PROTEIN/PHENOLOXIDASE; 1.
DR PANTHER; PTHR11511:SF4; PHENOLOXIDASE 2-RELATED; 1.
DR Pfam; PF03723; Hemocyanin_C; 1.
DR Pfam; PF00372; Hemocyanin_M; 1.
DR Pfam; PF03722; Hemocyanin_N; 1.
DR PRINTS; PR00187; HAEMOCYANIN.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF48050; Hemocyanin, N-terminal domain; 1.
DR PROSITE; PS00210; HEMOCYANIN_2; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 386..397
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 679 AA; 77371 MW; 399479F9A3CB6572 CRC64;
MAGDQNVVLD LFEHPYSKKG PPRTAAEARP IVFEDDVTTR VGGGPPAPGP LTLARSVPRG
SVFSSFVREH RLAARELCDY LMQATNVREL SLMAEEVRRE LNEKLFIYAV SFVILRKPEM
RAMRLPSIVE VFPSCFVPRT TLATMEQQAR QPSTTGQDVI ITEYGPEFSS THLKPEHRVA
YWREDYGINL HHWHWHLVYP LDMGVDRDRK GELFYYMHQQ MLARYDMDRL SVGLNRVEKL
ANWRMPIPDG YFSKLTLDNS GQVWGSRQDG TLLQEYRRNE FMLEPFDVTD LEQHHSRLMD
AIHQGHLIDR EGKRVRLTDE GVAPNRRGIV LLGDALEADA GLSVNSPFYG DLHNSGHVII
AAAHDPDNAH RENLGVMSDT STAMRDPVFY RWHKYIDDLF QEYKLTQPPY TMEQLSVQTV
TVAGVEVESV GSKNTLTTGW NTRDFEASRG LDFNSSIPVM VRLTHLDHRP FRYNIKVENN
GKVAKDVTVR IFMAPKLNER GVRMNIMEQR LLWAEMDRFK HTLKPGTNTV SRESTASSIT
NPNDFTFGDL SNLPVPDNPG APENDLFNFC GCGWPQHMLL PRGKQEGMDF QLFVMVTDWK
LDKVAQPAGR RSCANAASFC GVLDALYPDA RPMGFPFDRR PMPMLNGQSL DRAEDLTRLS
NVAMQEIQIV FTNAQLKEQ
//
