ID   B1W160_STRGG            Unreviewed;       332 AA.
AC   B1W160;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Putative reductase {ECO:0000313|EMBL:BAG19085.1};
GN   OrderedLocusNames=SGR_2256 {ECO:0000313|EMBL:BAG19085.1};
OS   Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=455632 {ECO:0000313|EMBL:BAG19085.1, ECO:0000313|Proteomes:UP000001685};
RN   [1] {ECO:0000313|EMBL:BAG19085.1, ECO:0000313|Proteomes:UP000001685}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 4626 / NBRC 13350 {ECO:0000313|Proteomes:UP000001685};
RX   PubMed=18375553; DOI=10.1128/JB.00204-08;
RA   Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H.,
RA   Yamashita A., Hattori M., Horinouchi S.;
RT   "Genome sequence of the streptomycin-producing microorganism Streptomyces
RT   griseus IFO 13350.";
RL   J. Bacteriol. 190:4050-4060(2008).
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DR   EMBL; AP009493; BAG19085.1; -; Genomic_DNA.
DR   AlphaFoldDB; B1W160; -.
DR   KEGG; sgr:SGR_2256; -.
DR   eggNOG; COG0451; Bacteria.
DR   HOGENOM; CLU_061176_0_0_11; -.
DR   Proteomes; UP000001685; Chromosome.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF49; HREPIB; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          4..206
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   332 AA;  35094 MW;  5EB7A127E7332374 CRC64;
     MRLLMLGGTE FVGRAVTDAA LARGWDVTVF HRGRHAPPPG ARTLTGDRTA GERGLAALAE
     SVRDWDLVVD TWSGAPAAVR DAARLLSGRA GHFSYVSSRS VYAHPAAPGL DEDGPLVAGA
     SPDDGAGVPY DRAKRGGELA ALDAFGDRAL LARAGLIIGP GENIGRLPWW LSRIARGGPV
     IAPGRPGTEL QYIDARDLAA WILDAAAGGL HGAYNTVSRP GHTTTGELLE SCVRVTGSDA
     ELRWTEPEVL LAAGVEPWTD LPIWLPPGEL YDTLHRGDST RAYAAGLRCR PAAETVADTW
     TWLRGLGGVA PRRPDRPAVG LDPRLEAKLL AL
//