ID MATA_ECODH Reviewed; 196 AA.
AC B1XE36;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 1.
DT 01-MAY-2013, entry version 42.
DE RecName: Full=HTH-type transcriptional regulator MatA;
GN Name=matA; OrderedLocusNames=ECDH10B_0282;
OS Escherichia coli (strain K12 / DH10B).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=316385;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / DH10B;
RX PubMed=18245285; DOI=10.1128/JB.01695-07;
RA Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B.,
RA Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B.,
RA Posfai G., Weinstock G.M., Blattner F.R.;
RT "The complete genome sequence of Escherichia coli DH10B: insights into
RT the biology of a laboratory workhorse.";
RL J. Bacteriol. 190:2597-2606(2008).
CC -!- FUNCTION: Represses expression of the flagellar master operon
CC flhDC, and consequently prevents flagellum biosynthesis and
CC motility. Acts by binding to the regulatory region of the flhDC
CC operon (By similarity).
CC -!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
CC -!- SIMILARITY: Belongs to the MatA family.
CC -!- SIMILARITY: Contains 1 HTH luxR-type DNA-binding domain.
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DR EMBL; CP000948; ACB01460.1; -; Genomic_DNA.
DR RefSeq; YP_001729238.1; NC_010473.1.
DR ProteinModelPortal; B1XE36; -.
DR SMR; B1XE36; 144-188.
DR STRING; 316385.ECDH10B_0282; -.
DR EnsemblBacteria; ACB01460; ACB01460; ECDH10B_0282.
DR GeneID; 6058216; -.
DR KEGG; ecd:ECDH10B_0282; -.
DR PATRIC; 18460320; VBIEscCol59506_0278.
DR eggNOG; COG2771; -.
DR HOGENOM; HOG000059412; -.
DR OMA; RDYEVEN; -.
DR ProtClustDB; CLSK2750822; -.
DR BioCyc; ECOL316385:GJ8B-278-MONOMER; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:GOC.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR011991; WHTH_DNA-bd_dom.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; Bipartite_resp_reg_C-effector; 1.
DR PROSITE; PS00622; HTH_LUXR_1; FALSE_NEG.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 3: Inferred from homology;
KW Complete proteome; Cytoplasm; DNA-binding; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1 196 HTH-type transcriptional regulator MatA.
FT /FTId=PRO_0000369174.
FT DOMAIN 138 196 HTH luxR-type.
FT DNA_BIND 162 181 H-T-H motif (By similarity).
SQ SEQUENCE 196 AA; 23274 MW; 5A3676E17E9793B9 CRC64;
MTWQSDYSRD YEVKNHMECQ NRSDKYIWSP HDAYFYKGLS ELIVDIDRLI YLSLEKIRKD
FVFINLSTDS LSEFINRDNE WLSAVKGKQV VLIAARKSEA LANYWYYNSN IRGVVYAGLS
RDIRKELVYV INGRFLRKDI KKDKITDREM EIIRMTAQGM QPKSIARIEN CSVKTVYTHR
RNAEAKLYSK IYKLVQ
//
