ID B1YEV5_EXIS2 Unreviewed; 907 AA.
AC B1YEV5;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=5'-Nucleotidase domain protein {ECO:0000313|EMBL:ACB60713.1};
GN OrderedLocusNames=Exig_1235 {ECO:0000313|EMBL:ACB60713.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB60713.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB60713.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB60713.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001022; ACB60713.1; -; Genomic_DNA.
DR RefSeq; WP_012370134.1; NC_010556.1.
DR AlphaFoldDB; B1YEV5; -.
DR STRING; 262543.Exig_1235; -.
DR KEGG; esi:Exig_1235; -.
DR eggNOG; COG0737; Bacteria.
DR HOGENOM; CLU_005854_4_1_9; -.
DR OrthoDB; 9775118at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008252; F:nucleotidase activity; IEA:UniProt.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR InterPro; IPR008334; 5'-Nucleotdase_C.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR006146; 5'-Nucleotdase_CS.
DR InterPro; IPR006179; 5_nucleotidase/apyrase.
DR InterPro; IPR041498; Big_6.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR11575:SF6; 2',3'-CYCLIC-NUCLEOTIDE 2'-PHOSPHODIESTERASE_3'-NUCLEOTIDASE; 1.
DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR Pfam; PF02872; 5_nucleotid_C; 1.
DR Pfam; PF17936; Big_6; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR01607; APYRASEFAMLY.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS00786; 5_NUCLEOTIDASE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001681}.
FT DOMAIN 36..285
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 377..572
FT /note="5'-Nucleotidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02872"
FT DOMAIN 670..727
FT /note="Bacterial Ig"
FT /evidence="ECO:0000259|Pfam:PF17936"
SQ SEQUENCE 907 AA; 98835 MW; 598D8EF82C0724A6 CRC64;
MKQITKIVIA STLIAPMLAP VIQVKTLAAD NSVVKLRFLE TTDLHTNSMN YDYFKDVQDE
TIGLVKAATV IKQEQNVVGE DNSFVFDNGD TLQGTPFGDY VKNQYDKGDK GKHPMYELME
YIGYDAVTLG NHEFNFGLDF LKSAMKASSG EIKFVNSNVL DAVTKKPIVS EFNTDGKDYQ
IIERQVKDQN GQMKTVKVGV FGVVAPQIMA WDAGNLTGKV TAEDIVPVAK ATAKKLKDAG
ADVVVALAHT GIGDTADQKD GDENVGYALT KIADIDVLMT GHQHGKFPDA KSAFNGLPNV
DKTNGLINGK PVVMANTQGK NVGVIDLQLK HDGGKWVVDT AGAKLADVTK DTTADAGAVK
LIEKAHEGTL AYIRQQVGTI NDDIQSFFAL VKDDDSVQFV TNAQKWYVEK QLKENADLAQ
YKDLPLLSAG APFKTGGRLQ LNASEYTLIK KGPIALKNVA DLYVYPNTLE VVKVTGADIK
DWLEMSAGQF NEVSDQQQSL LNPEFRSYNF DILDGLTYDI DITKPAKYTY EGELSKTYKG
DDRVLNIKYQ GKEIKDDQEF LVATNNYRAG SATFPGLGQG KKIVYKSAYE TRNVISDFIK
AKQPVDYQAD NNWSLVASKP ITVDFDSAEA AADYTNRYEG ITNTGIKRAG DTGTFLKFKL
DVPMKDFNVS VSAVKPGAKV VTGKAVAGAK VTVKRGTTVL GTATADETGK YAVTVRPVKL
RDKLTVVSEL GFMKKETTVT VGTGVVATPA IDKKSAVYGS TVLTGKATEG LDVTLYKGST
KIAKAKTTAS GFKIPVKNGL MTGTYTVKST DISNKITKKA SFTIKNTYPV KKWAGKKTLT
GKVEKRQIVR LFEKTSSGYK LIAQDVADNH GNYVLKMRTG LATGSYKMNI YTASDRLDQS
RYFITKK
//
