ID B1YHN4_EXIS2 Unreviewed; 505 AA.
AC B1YHN4;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Substrate-binding region of ABC-type glycine betaine transport system {ECO:0000313|EMBL:ACB61207.1};
GN OrderedLocusNames=Exig_1755 {ECO:0000313|EMBL:ACB61207.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB61207.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB61207.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB61207.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OsmX family.
CC {ECO:0000256|ARBA:ARBA00035642}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the binding-protein-
CC dependent transport system permease family.
CC {ECO:0000256|ARBA:ARBA00035652}.
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DR EMBL; CP001022; ACB61207.1; -; Genomic_DNA.
DR RefSeq; WP_012370625.1; NC_010556.1.
DR AlphaFoldDB; B1YHN4; -.
DR STRING; 262543.Exig_1755; -.
DR KEGG; esi:Exig_1755; -.
DR eggNOG; COG1174; Bacteria.
DR eggNOG; COG1732; Bacteria.
DR HOGENOM; CLU_038355_0_1_9; -.
DR OrthoDB; 9801163at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd13610; PBP2_ChoS; 1.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 1.
DR InterPro; IPR007210; ABC_Gly_betaine_transp_sub-bd.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR30177; GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR PANTHER; PTHR30177:SF4; OSMOPROTECTANT IMPORT PERMEASE PROTEIN OSMW; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF04069; OpuAC; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000001681};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032}; Transport {ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 23..45
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 66..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 147..172
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 19..198
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 505 AA; 55217 MW; BB3AD3CBF2FF2A8B CRC64;
MTGLFETYQD RKTELLQALI EHIQLSVLSL VIACVIAIPL GIYLSRHKKF SEWSIGVTSV
IQTIPSLALL GLMIPLVGIG TVPSVIALVL YALLPIVRNT YTGLAEVDPS LKEAARACGM
TPMQSLMKVE LPLALPVMMA GIRTAMVLII GTATIAALIG AGGLGSIILL GIDRNDNYLL
LLGAIPAALL ALLFDGLLRQ TEVATKKRQT GRLVVALALI AALIITPFAL GRTEQPDLVV
AGKLGVEPEI LMNMYKLVIE DQTDLNVQVK PNFGKTTFVY KALQSGDIDL YPEFTGTVLA
SLTNEKPVSN DKQAVFEQAR DGLAKQKLAL LPPMNYNNTY AVAVPKKVAD QYQLKTISDL
QQVADQLKAG FTLEFKDRQD GYKGIQEKYG VNFKEVVTME PKLRYKAVQS GDIQVIDAYS
TDPEIAKYNM VVLEDDQQLF PPYEGAPLLR QETLDEYPEV EQALKQLNGK ISDSEMSKMN
EAVAYGGKTA NQVARDYLQK EGILK
//
