ID   B1Z8B7_METPB            Unreviewed;       464 AA.
AC   B1Z8B7;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   RecName: Full=8-amino-7-oxononanoate synthase {ECO:0000256|ARBA:ARBA00016004};
DE   AltName: Full=Alpha-oxoamine synthase {ECO:0000256|ARBA:ARBA00031658};
GN   OrderedLocusNames=Mpop_2275 {ECO:0000313|EMBL:ACB80437.1};
OS   Methylorubrum populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)
OS   (Methylobacterium populi).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=441620 {ECO:0000313|EMBL:ACB80437.1, ECO:0000313|Proteomes:UP000007136};
RN   [1] {ECO:0000313|EMBL:ACB80437.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BJ001 {ECO:0000313|EMBL:ACB80437.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Marx C., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium populi BJ001.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC       pyridoxal-phosphate-dependent aminotransferase family.
CC       {ECO:0000256|ARBA:ARBA00005384}.
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DR   EMBL; CP001029; ACB80437.1; -; Genomic_DNA.
DR   RefSeq; WP_012454171.1; NC_010725.1.
DR   AlphaFoldDB; B1Z8B7; -.
DR   STRING; 441620.Mpop_2275; -.
DR   KEGG; mpo:Mpop_2275; -.
DR   eggNOG; COG1167; Bacteria.
DR   HOGENOM; CLU_017584_0_0_5; -.
DR   OrthoDB; 9802328at2; -.
DR   Proteomes; UP000007136; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   PANTHER; PTHR46577:SF2; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:ACB80437.1};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transferase {ECO:0000313|EMBL:ACB80437.1}.
FT   DOMAIN          10..78
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   464 AA;  50580 MW;  2EA3E16720649E65 CRC64;
     MTVMVAEPVL SRVETVMRAI EARIEGRALG PGARLPSVRG LAESMQVSKS TVVEAYDRLA
     ARGAIVSRPG SGFFVSARPE PLSLTAIGPR LDRAVDPVWI TRQSLEARPD SLRPGCGWLP
     PDWLPQAELR RALRQVARQS DAVMFYDTPQ GHAPLRQHMA LRLTERGIRA HPDQLVLTDS
     VTHALDLIIR FLAEPGDTVL LDDPCYFSFQ ALARAHRLHM VGVPFGPEGP DLAAFEQALI
     EHRPRFYITN SGLQNPTGAS LSPVVVHRIL RLAEMHGTLI VEDDAYADFE AEPGPRLAGF
     DGLDRVIHVG GFSKTISTGA RLGAIAIRDD WVERLVDLKL AVSLSDNHLT AATLHRFLGD
     GSYRHHVDAM RTRLAEARGT VVRRLAEVGV TVPFVPKAGM FLWARLPDGL DAAAVSRRAL
     ARGVVLAPGN VFSLSQGAAD AMRFNVAQCA DPRVFSELSR AMEG
//