ID   B1ZS02_OPITP            Unreviewed;       810 AA.
AC   B1ZS02;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Immunoglobulin I-set domain protein {ECO:0000313|EMBL:ACB74678.1};
GN   OrderedLocusNames=Oter_1393 {ECO:0000313|EMBL:ACB74678.1};
OS   Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1).
OC   Bacteria; Verrucomicrobiota; Opitutae; Opitutales; Opitutaceae; Opitutus.
OX   NCBI_TaxID=452637 {ECO:0000313|EMBL:ACB74678.1, ECO:0000313|Proteomes:UP000007013};
RN   [1] {ECO:0000313|EMBL:ACB74678.1, ECO:0000313|Proteomes:UP000007013}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11246 / JCM 15787 / PB90-1
RC   {ECO:0000313|Proteomes:UP000007013};
RX   PubMed=21398538; DOI=10.1128/JB.00228-11;
RA   van Passel M.W., Kant R., Palva A., Copeland A., Lucas S., Lapidus A.,
RA   Glavina del Rio T., Pitluck S., Goltsman E., Clum A., Sun H., Schmutz J.,
RA   Larimer F.W., Land M.L., Hauser L., Kyrpides N., Mikhailova N.,
RA   Richardson P.P., Janssen P.H., de Vos W.M., Smidt H.;
RT   "Genome sequence of the verrucomicrobium Opitutus terrae PB90-1, an
RT   abundant inhabitant of rice paddy soil ecosystems.";
RL   J. Bacteriol. 193:2367-2368(2011).
CC   -!- PATHWAY: Glycan metabolism; L-arabinan degradation.
CC       {ECO:0000256|ARBA:ARBA00004834}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC       {ECO:0000256|ARBA:ARBA00009865}.
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DR   EMBL; CP001032; ACB74678.1; -; Genomic_DNA.
DR   AlphaFoldDB; B1ZS02; -.
DR   STRING; 452637.Oter_1393; -.
DR   CAZy; GH43; Glycoside Hydrolase Family 43.
DR   KEGG; ote:Oter_1393; -.
DR   eggNOG; COG3507; Bacteria.
DR   HOGENOM; CLU_348094_0_0_0; -.
DR   OrthoDB; 9801455at2; -.
DR   Proteomes; UP000007013; Chromosome.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd18832; GH43_GsAbnA-like; 1.
DR   Gene3D; 2.40.128.10; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR032291; Abn2_C.
DR   InterPro; IPR006710; Glyco_hydro_43.
DR   InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   PANTHER; PTHR43301; ARABINAN ENDO-1,5-ALPHA-L-ARABINOSIDASE; 1.
DR   PANTHER; PTHR43301:SF3; ARABINOSIDASE-RELATED; 1.
DR   Pfam; PF16369; GH43_C; 1.
DR   Pfam; PF04616; Glyco_hydro_43; 1.
DR   Pfam; PF13927; Ig_3; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00408; IGc2; 1.
DR   SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007013}.
FT   DOMAIN          468..548
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   ACT_SITE        27
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT   ACT_SITE        215
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT   SITE            157
FT                   /note="Important for catalytic activity, responsible for
FT                   pKa modulation of the active site Glu and correct
FT                   orientation of both the proton donor and substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ   SEQUENCE   810 AA;  85327 MW;  D6FF69DEF98C2909 CRC64;
     MLGALMLGAV SAQPLPTPTF TNVTVHDPSV IKAGARWYVY GSHGASAWTE DLMHWTQVAT
     SVTSGNPAHF NTFASELSEL IDWTHADTLW APDVVQLPDG KFYYYYDVWT NYLNYRSYMG
     LASADGIEGP FTDVGEIMKG GTNVSGFDPA IHPNTIDPDV FYDRDGQLWM VYGSYSGGIF
     ILRLDQTVGS ATFGRPLPGQ SWGTKLIGGN HARIEGPCII YSPESQYYYL FLSFGGLAAN
     DGYNIRVARS RNPDGPYVDA AGNDLKNVGG SDAAIAPYGV KLIGNYQFAH VAGEPRNTSR
     GYLSPGHNSV YRDPATGKYF LLFHTRFVGL GETHEVRVHQ MFLNADGWFV VAPQRYAGET
     IAPITARQVP GSFKLINHGW VISSAVNGSS LITLNADGTI SGSVSGTWQV TGDNSVTLSY
     NGANYRGVFV LQWDDDNQVW ILGFTALSAD GTAIWGSKVA ALNAVAAPAL TGTPSSQTVA
     AGGTATLTAA ASGVPAPELQ WERNGSAVVG ANSTVLTLAN LAPADAGIYT IDASNFAGSA
     PSAPAIVGLT SAAKVIGTGE ELTPVDIHHP NGNIFDQVLL TGAAETITAD AGQVTRTSYI
     DLDNDIVQVE FSGPGSLSLV LDNASGRAKP ENYNQDIDYM KGHAGIVITG ATENTHVSVF
     SVGRATAVNQ ALFKDTVNYD GIADIAFIAI SSSNGRFGGV RTANANYFAS RGVTGVYAPG
     VAFDGPVFVG NITAFDAAQP KIVLGSVSDA RIAGGDLYQD NGAAVQVSGI TQLKFTNGSD
     SHGNTILAKA NRAVLQENGE DVTNRIVTGP
//