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Database: UniProt
Entry: B1ZZL9
LinkDB: B1ZZL9
Original site: B1ZZL9 
ID   DNLI_OPITP              Reviewed;        1017 AA.
AC   B1ZZL9;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-OCT-2017, entry version 68.
DE   RecName: Full=Probable DNA ligase;
DE            EC=6.5.1.1 {ECO:0000255|PROSITE-ProRule:PRU10135};
DE   AltName: Full=Polydeoxyribonucleotide synthase [ATP];
GN   Name=lig; OrderedLocusNames=Oter_3148;
OS   Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1).
OC   Bacteria; Verrucomicrobia; Opitutae; Opitutales; Opitutaceae;
OC   Opitutus.
OX   NCBI_TaxID=452637;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11246 / JCM 15787 / PB90-1;
RX   PubMed=21398538; DOI=10.1128/JB.00228-11;
RA   van Passel M.W., Kant R., Palva A., Copeland A., Lucas S., Lapidus A.,
RA   Glavina del Rio T., Pitluck S., Goltsman E., Clum A., Sun H.,
RA   Schmutz J., Larimer F.W., Land M.L., Hauser L., Kyrpides N.,
RA   Mikhailova N., Richardson P.P., Janssen P.H., de Vos W.M., Smidt H.;
RT   "Genome sequence of the verrucomicrobium Opitutus terrae PB90-1, an
RT   abundant inhabitant of rice paddy soil ecosystems.";
RL   J. Bacteriol. 193:2367-2368(2011).
CC   -!- FUNCTION: DNA ligase that seals nicks in double-stranded DNA
CC       during DNA replication, DNA recombination and DNA repair.
CC       {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000255|PROSITE-ProRule:PRU10135}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: In the C-terminal section; belongs to the ATP-
CC       dependent DNA ligase family. {ECO:0000305}.
DR   EMBL; CP001032; ACB76428.1; -; Genomic_DNA.
DR   RefSeq; WP_012375957.1; NC_010571.1.
DR   ProteinModelPortal; B1ZZL9; -.
DR   SMR; B1ZZL9; -.
DR   STRING; 452637.Oter_3148; -.
DR   EnsemblBacteria; ACB76428; ACB76428; Oter_3148.
DR   KEGG; ote:Oter_3148; -.
DR   eggNOG; ENOG4107T0X; Bacteria.
DR   eggNOG; COG1236; LUCA.
DR   eggNOG; COG1793; LUCA.
DR   KO; K10747; -.
DR   OrthoDB; POG091H09SJ; -.
DR   Proteomes; UP000007013; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.60.15.10; -; 2.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR036866; Metallo-hydrolase/OxRdtase.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR011108; RMMBL.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   Pfam; PF07521; RMMBL; 1.
DR   SUPFAM; SSF117018; SSF117018; 2.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS00333; DNA_LIGASE_A2; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell cycle; Cell division; Complete proteome; DNA damage;
KW   DNA recombination; DNA repair; DNA replication; Ligase; Magnesium;
KW   Metal-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN         1   1017       Probable DNA ligase.
FT                                /FTId=PRO_0000365242.
FT   REGION        1    363       Unknown.
FT   REGION      364   1017       DNA ligase.
FT   ACT_SITE    669    669       N6-AMP-lysine intermediate.
FT                                {ECO:0000255|PROSITE-ProRule:PRU10135}.
FT   BINDING     667    667       ATP. {ECO:0000250}.
FT   BINDING     674    674       ATP. {ECO:0000250}.
FT   BINDING     689    689       ATP. {ECO:0000250}.
FT   BINDING     717    717       ATP. {ECO:0000250}.
FT   BINDING     860    860       ATP. {ECO:0000250}.
FT   BINDING     866    866       ATP. {ECO:0000250}.
SQ   SEQUENCE   1017 AA;  109840 MW;  F2D76752C20C30B9 CRC64;
     MPWDVKFSHG LYLPQLGWWL DAHFPQKRSF VSHAHSDHTA THDEILCSAG TAALMRARLD
     AKRIEHVLPF GQTEQLTADC GVTLHPAGHI FGSAQCLLEH GEHGSLLYTG DFKLRRGRSA
     EPCATPHAEL VIMETTFGRP HYVFPPTAQV LNDIATFCHE TIADDGVPVL FGYSLGKSQE
     LLCSLEESQL PVMLHPQTHK LTRVYEQFGI AFPPYREFDL ATVRGHVVIC PPQSRESAFV
     RRIPGHRTAM ITGWAMDPGA IYRYQCDAAF PLSDHADYQD LLRFVEAVNP QRVLTLHGFA
     TEFAQTLRER GLEAWAIGED NQLELGIRSS PPQVRAGDAT PSSRSSGDAG VAAPACATPL
     HAPDSFARFV AAADAVKATP KKLEKIAVLR DYLAALTPPD MGTAATFLTG RAFPQRDPRN
     LTLGWSVIKR AVLEVAGVTE ADYRDAYHRF ADTGDAAGAV LAQRSLRPGD ATPSSRPEIL
     GVAGVADPGP AASRPAATSA PTTCSLADMA LFFERAAAAR GPAAKLDLLR ERLALITPDE
     ARYLIKIITG DLRIGLKEGL VEEALAAAAG QPLEAVREAA MLCGDIAAVA RAARTDTLAE
     IQLTVFNPLQ FMLASPEPTA EAIVDRFAAQ RTAEAAAIVA GVGDPGPGSS SPATADAAPA
     LARIWLEEKY DGIRCQLHKS GGRVELYSRD LNVITEQFPD LARAALALPH DFIGDGELLA
     WRDGRALPFA ELQKRLGRKG GDDFFLGAEI PVSISFYDLL WLDGRSLLKE PLRERRALLE
     RLLHGDATPS SRPDGDEGVA APALQPATLN PQLSTKFSLA PVTFAHTASD IEAAFLAARQ
     RGNEGLMAKD PASGYTPGRR GLAWLKLKKA YATLDVVVVG VEYGHGKRRD VLSDYTFAIR
     DEEHDNQLLT VGKAYSGLTD VEIAQLTQHF LEHTLEVHGR YRVVVPDTVI EVAFDTIQPS
     SRHQSGFALR FPRIARIRTD KTPAEIDTLA TCRKLAAAAG SGGIAAVGAR PPPAASD
//
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