ID   B2BYD6_PLAVI            Unreviewed;       347 AA.
AC   B2BYD6;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Dihydropteroate synthase {ECO:0000313|EMBL:ABY51996.1};
DE   Flags: Fragment;
GN   Name=dhps {ECO:0000313|EMBL:ABY51996.1};
OS   Plasmodium vivax (malaria parasite P. vivax).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX   NCBI_TaxID=5855 {ECO:0000313|EMBL:ABY51996.1};
RN   [1] {ECO:0000313|EMBL:ABY51996.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MIA06N38618 {ECO:0000313|EMBL:ABY51996.1};
RX   PubMed=18302746; DOI=10.1186/1475-2875-7-35;
RA   Barnadas C., Tichit M., Bouchier C., Ratsimbasoa A., Randrianasolo L.,
RA   Raherinjafy R., Jahevitra M., Picot S., Menard D.;
RT   "Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and
RT   therapeutic response to sulphadoxine-pyrimethamine.";
RL   Malar. J. 7:35-35(2008).
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DR   EMBL; EU177001; ABY51996.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2BYD6; -.
DR   HOGENOM; CLU_391048_0_0_1; -.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR   GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR   InterPro; IPR045031; DHP_synth-like.
DR   InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR   InterPro; IPR000489; Pterin-binding_dom.
DR   PANTHER; PTHR20941; FOLATE SYNTHESIS PROTEINS; 1.
DR   PANTHER; PTHR20941:SF1; FOLIC ACID SYNTHESIS PROTEIN FOL1; 1.
DR   Pfam; PF00809; Pterin_bind; 1.
DR   SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR   PROSITE; PS00793; DHPS_2; 1.
DR   PROSITE; PS50972; PTERIN_BINDING; 1.
PE   4: Predicted;
FT   DOMAIN          1..347
FT                   /note="Pterin-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50972"
FT   REGION          257..287
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..287
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ABY51996.1"
FT   NON_TER         347
FT                   /evidence="ECO:0000313|EMBL:ABY51996.1"
SQ   SEQUENCE   347 AA;  38767 MW;  374AF6A8877D32D3 CRC64;
     AVERMFEMAS DGASVIDIGG ESSAPYVVPN PSVTERDLVM PVLKLFKEEW HKLECEVGGG
     AVCCAAASDA RKNAQSSLQG KLQKVRDAKP IISIDTVNYD LFKECVEGEL VDILNDISAC
     THNPEIIKLL RRKNKFYSVV LMHKRGNPHT MDKLTNYDDL ISDIKRYLED RLHFLVLNGV
     PRYRVLFDVG LGFAKKHDQS IKLLQHIHVY DEYPLFLGYS RKRFIVHCMG KGGAAIGECR
     LMSGEAKLTN GEGKLTNGEG KLTNGEAKLT NGEGKLTNGD SKLTNGEAKL TNGDPSQLWR
     FKMSHMRQDK DQLLYQKNIC GGLAIASYSF YKKVDLIRVH DVLETKA
//