ID B2FQC3_STRMK Unreviewed; 702 AA.
AC B2FQC3;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:CAQ45768.1};
GN OrderedLocusNames=Smlt2273 {ECO:0000313|EMBL:CAQ45768.1};
OS Stenotrophomonas maltophilia (strain K279a).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Stenotrophomonas; Stenotrophomonas maltophilia group.
OX NCBI_TaxID=522373 {ECO:0000313|EMBL:CAQ45768.1, ECO:0000313|Proteomes:UP000008840};
RN [1] {ECO:0000313|EMBL:CAQ45768.1, ECO:0000313|Proteomes:UP000008840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K279a {ECO:0000313|EMBL:CAQ45768.1,
RC ECO:0000313|Proteomes:UP000008840};
RX PubMed=18419807; DOI=10.1186/gb-2008-9-4-r74;
RA Crossman L.C., Gould V.C., Dow J.M., Vernikos G.S., Okazaki A.,
RA Sebaihia M., Saunders D., Arrowsmith C., Carver T., Peters N., Adlem E.,
RA Kerhornou A., Lord A., Murphy L., Seeger K., Squares R., Rutter S.,
RA Quail M.A., Rajandream M.A., Harris D., Churcher C., Bentley S.D.,
RA Parkhill J., Thomson N.R., Avison M.B.;
RT "The complete genome, comparative and functional analysis of
RT Stenotrophomonas maltophilia reveals an organism heavily shielded by drug
RT resistance determinants.";
RL Genome Biol. 9:R74.1-R74.13(2008).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; AM743169; CAQ45768.1; -; Genomic_DNA.
DR AlphaFoldDB; B2FQC3; -.
DR EnsemblBacteria; CAQ45768; CAQ45768; Smlt2273.
DR KEGG; sml:Smlt2273; -.
DR PATRIC; fig|522373.3.peg.2168; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_6; -.
DR Proteomes; UP000008840; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:CAQ45768.1};
KW Cilium {ECO:0000313|EMBL:CAQ45768.1};
KW Flagellum {ECO:0000313|EMBL:CAQ45768.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000008840};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 47..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 117..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 209..231
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 251..268
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 289..305
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 702 AA; 74373 MW; B875DBF7FF72EA32 CRC64;
MSAQPSAGFN TRRALEMIRQ GLGAPLIVLA LLAMVVVPLA APVLDALFTF NIAISLMVLL
AVVYVKRPLD FTIFPIVLLI TTMLRLALNV ASTRVILLNG QNGHDAAGKV IAAFGEFVIG
GNYAVGIVVF AILTIINFVV ITKGAGRVSE VTARFILDAM PGKQMAIDAD LNAGLLTREE
AKLRREEVRE EADFYGAMDG ASKFIRGDAI AGILILFINM LGGLAVGVLQ HGMPFGEAAA
TYTLLSIGDG LVAQLPALLV SSAVAMLVTR ASRSQDMAQA MTGQVFGQYR ALAITAGIIG
VVGLVPGMPN VAFLTLAAIL GFIAWKVYRK GKAAATDPAA AGNDAAALNA LGRPAAPAPT
AELSWDELRP VDPLGLEVGY RLIPLVDSNQ GGELMARIKG VRRKLTQDVG FLIPSVHIRD
NLELPANGYR VLVHGVPVAT AEIHPDRELA LDPGSALGTL EGIAGKDPAF GLDATWIQPH
QRAQAETLGY TVVDPATVVA THLSHLIREH APELLGHEEV QHLLANLAKS APKLVEDLTP
KALPLSAVVR VLQNLLVERI PIRQLRKIAE ALVEHAPSSQ DPAVLTAAVR TALGRFIVQE
IAGMSAELPV FTLNPQLERV LQESTQGNGA ALEPGLAERL HQSLAECVSK QEARNEPAVV
LVPGPVRAAL ARLVRHSVPS LSVLAYSEVP EDKRLKLVGT IS
//
