ID   B2FYI5_ANOGA            Unreviewed;       186 AA.
AC   B2FYI5;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=CLIPA8 protein {ECO:0000313|EMBL:CAO84324.1};
DE   Flags: Fragment;
GN   Name=clipa8 {ECO:0000313|EMBL:CAO84324.1};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|EMBL:CAO84324.1};
RN   [1] {ECO:0000313|EMBL:CAO84324.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=S4 {ECO:0000313|EMBL:CAO84324.1}, and S7
RC   {ECO:0000313|EMBL:CAO84327.1};
RA   Cohuet A., Krishnakumar S., Simard F., Morlais I., Koutsos A.,
RA   Fontenille D., Mindrinos M., Kafatos F.C.;
RT   "Genetic diversity and adaptive evolution in Anopheles gambiae innate
RT   immune system.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. CLIP subfamily.
CC       {ECO:0000256|ARBA:ARBA00024195}.
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DR   EMBL; AM775866; CAO84324.1; -; mRNA.
DR   EMBL; AM775869; CAO84327.1; -; mRNA.
DR   AlphaFoldDB; B2FYI5; -.
DR   VEuPathDB; VectorBase:AGAP010731; -.
DR   HOGENOM; CLU_006842_0_3_1; -.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR041515; PPAF-2-like_Clip.
DR   InterPro; IPR001254; Trypsin_dom.
DR   PANTHER; PTHR24260; -; 1.
DR   PANTHER; PTHR24260:SF151; GH21666P-RELATED; 1.
DR   Pfam; PF18322; CLIP_1; 1.
DR   Pfam; PF00089; Trypsin; 1.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157}.
FT   DOMAIN          3..44
FT                   /note="PPAF-2-like Clip"
FT                   /evidence="ECO:0000259|Pfam:PF18322"
FT   DOMAIN          83..184
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|Pfam:PF00089"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAO84324.1"
FT   NON_TER         186
FT                   /evidence="ECO:0000313|EMBL:CAO84324.1"
SQ   SEQUENCE   186 AA;  21026 MW;  A9167EE7DD03E2E1 CRC64;
     GFCSPKYLCP NGTYNEANAQ NQEIIMLRFG EEDVCQDYMQ VCCSNATSMR YELVTNNEPV
     EYGCGISNPG GLIYQVEGNR TYAQYGEFPW VVAILEAFYS SNEQQFTYVG GGTLIHPRFV
     VTAAHIFNKT ENLVASFGEW DMNRDENVYP KQNIDIDRTI IVHPEYSSVG LLNDIALAQL
     KQNVVY
//