ID B2GHG5_KOCRD Unreviewed; 571 AA.
AC B2GHG5;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Putative fatty-acid--CoA ligase {ECO:0000313|EMBL:BAG30441.1};
DE EC=6.2.1.- {ECO:0000313|EMBL:BAG30441.1};
GN OrderedLocusNames=KRH_20940 {ECO:0000313|EMBL:BAG30441.1};
OS Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Kocuria.
OX NCBI_TaxID=378753 {ECO:0000313|EMBL:BAG30441.1, ECO:0000313|Proteomes:UP000008838};
RN [1] {ECO:0000313|EMBL:BAG30441.1, ECO:0000313|Proteomes:UP000008838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9341 / DSM 348 / NBRC 103217 / DC2201
RC {ECO:0000313|Proteomes:UP000008838};
RX PubMed=18408034; DOI=10.1128/JB.01853-07;
RA Takarada H., Sekine M., Kosugi H., Matsuo Y., Fujisawa T., Omata S.,
RA Kishi E., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT "Complete genome sequence of the soil actinomycete Kocuria rhizophila.";
RL J. Bacteriol. 190:4139-4146(2008).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; AP009152; BAG30441.1; -; Genomic_DNA.
DR RefSeq; WP_012399162.1; NC_010617.1.
DR AlphaFoldDB; B2GHG5; -.
DR STRING; 378753.KRH_20940; -.
DR KEGG; krh:KRH_20940; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_5_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000008838; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43859; ACYL-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR43859:SF4; BUTANOATE--COA LIGASE AAE1; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:BAG30441.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008838}.
FT DOMAIN 95..438
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 488..563
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 58..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 61899 MW; 53E76B3449602152 CRC64;
MFANTEPLTP LRFLERSAEV FPDRRAVVHG SQEWSYRQFD RDVQRFAAAL RPLLADAPAE
SSGATGEGDR SNGAGRRAAE EDFQGAEFLE REWPTVAVVA PNVPAALMAH YAVPAAGAVL
VPLNPRLSAR ELQYILEHCG ARVVLADVSV LDTVAEAMGD RTGVRLVQVP DEQAGLPAVR
DGAGAGVPTF EEFLDAPVRH AGSAEKTDGG VVRRGVVDEN APITLNYTSG TTGRPKGVLY
SHRGAYLNSL GEVFHNGFTG DTRYLWTLPM FHCNGWCTTW AVTAAGGTHV CLRAVRAQDV
WSAFDEHAIT HLCGAPAVCS TIVDAQEAHP LDRRIRITTA GAPPAPSIIE RLEQAGFDIV
HVYGLTEVFG PITICEPQEQ WAELPASERA RQMSRQGVAM IQAESARVVD PEMQDVPADG
ESLGEVVLRG NNVMIGYYRD VTATRKAFDG GWFHTGDLGV MHPNGYIQLT DRAKDVIISG
GENISSIEVE QALYSHPDVL DVAVVGVPHE KWGERPVAHV VRAGGSTVTE EQLREHVRSQ
LSGFKVPDSV TFTDELPRTA TGKVRKNLLR D
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