ID B2HL42_MYCMM Unreviewed; 364 AA.
AC B2HL42;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Plasmid maintenance system antidote protein {ECO:0000313|EMBL:ACC42018.1};
GN OrderedLocusNames=MMAR_3604 {ECO:0000313|EMBL:ACC42018.1};
OS Mycobacterium marinum (strain ATCC BAA-535 / M).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=216594 {ECO:0000313|EMBL:ACC42018.1, ECO:0000313|Proteomes:UP000001190};
RN [1] {ECO:0000313|EMBL:ACC42018.1, ECO:0000313|Proteomes:UP000001190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-535 / M {ECO:0000313|Proteomes:UP000001190};
RX PubMed=18403782; DOI=10.1101/gr.075069.107;
RA Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT "Insights from the complete genome sequence of Mycobacterium marinum on the
RT evolution of Mycobacterium tuberculosis.";
RL Genome Res. 18:729-741(2008).
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
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DR EMBL; CP000854; ACC42018.1; -; Genomic_DNA.
DR AlphaFoldDB; B2HL42; -.
DR STRING; 216594.MMAR_3604; -.
DR KEGG; mmi:MMAR_3604; -.
DR eggNOG; COG2856; Bacteria.
DR eggNOG; COG3093; Bacteria.
DR HOGENOM; CLU_055824_0_0_11; -.
DR OrthoDB; 9794834at2; -.
DR Proteomes; UP000001190; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR013430; Toxin_antidote_HigA.
DR NCBIfam; TIGR02607; antidote_HigA; 1.
DR PANTHER; PTHR36924; ANTITOXIN HIGA-1; 1.
DR PANTHER; PTHR36924:SF1; ANTITOXIN HIGA-1; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001190}.
FT DOMAIN 31..77
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 364 AA; 41149 MW; 3C942A55F443032A CRC64;
MPNHMNPTRA FQPDYASAPG ATVADMLDQV GMTQMELAQR LGVSPKHINQ VVKGVASISA
ELALGLEKVF GVSTAFWLNR QSLYRADIAR QKESRELASA LDWAKSFPVA ELRKRRLISS
STGPDLVNEL LHFFAIASPK LWSDPVAAYR KSQRFESDEK ALATWLRLGE IEAAAIECAP
FDNERFHEAV REARGLTRLN PAEWEPALIR ICAHAGVAVV IVDTFRGARA NGATRWLSPT
KALIQMSLRH RWEDIFWFSF FHEAAHVLLH GKKRIFIEGT GLPRDHSLQQ WEEEADRFAS
RTLVPPEHDH ELRRLTLTDI PTFAEQIGVD PGIVVGRLQH ERLIPNQRGN ELRHRLAFAE
QEPQ
//
