ID B2I9R3_XYLF2 Unreviewed; 555 AA.
AC B2I9R3;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=XfasM23_2036 {ECO:0000313|EMBL:ACB93434.1};
OS Xylella fastidiosa (strain M23).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Xylella.
OX NCBI_TaxID=405441 {ECO:0000313|EMBL:ACB93434.1, ECO:0000313|Proteomes:UP000001698};
RN [1] {ECO:0000313|EMBL:ACB93434.1, ECO:0000313|Proteomes:UP000001698}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M23 {ECO:0000313|EMBL:ACB93434.1,
RC ECO:0000313|Proteomes:UP000001698};
RX PubMed=20601474; DOI=10.1128/JB.00651-10;
RA Chen J., Xie G., Han S., Chertkov O., Sims D., Civerolo E.L.;
RT "Whole genome sequences of two Xylella fastidiosa strains (M12 and M23)
RT causing almond leaf scorch disease in California.";
RL J. Bacteriol. 192:4534-4534(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001011; ACB93434.1; -; Genomic_DNA.
DR AlphaFoldDB; B2I9R3; -.
DR KEGG; xfn:XfasM23_2036; -.
DR HOGENOM; CLU_000445_114_39_6; -.
DR Proteomes; UP000001698; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACB93434.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:ACB93434.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 340..550
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 555 AA; 61088 MW; 48B86C4BE3DBA559 CRC64;
MSPVVSILGY LSSALGHRDV LFSASLIHRI EFAPQRELYF LALYRILEAG LIAALVFSPV
SLLVDPESDP HLGTVVAVGY LLLATILLVW GRNERWFTPL VFGSTVADIL AATLAIHALP
KASAGIAMML LFNVAAAAIL LRLRFSMILA WIAGVAMLVE YIWTVLSEGD SSRSLAELLM
FFTSYTAVAY MCHQAAQRAR YSQALAEKRR AQIVNLAEIN ELIIRRMRTG VLVVDAANRI
GLSNETAAAL LGYDRQLVES DYDLATVAPE LIMRLKCWRI GRHYEDTPLR LAPDQPEVQP
RFVSLLADSG LTLIFLDDVS VVSRRAESLT LLALGRFSAS LAHEIRNPLA AIKHASQLLE
ESSNLDKGDQ RLLDIILKQC QRTNGIVESV LGLARRERAN PENLDLVGFV SRFVDEYRQT
LSSEYDNLEI QTLHSTVQAL VDPRHLYQIL AVLTHNALRY GRFPDTPAQV RIEVVYTGGS
VGINVLDQGP GIPDAAVLQL FQPFFTTSDH GTGLGLYIAR ELCNANQSNL EYVAIPGGGA
CFRITLPGPY ALIPN
//
