ID B2KIF7_RHIFE Unreviewed; 382 AA.
AC B2KIF7;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Apolipoprotein A-IV {ECO:0000256|ARBA:ARBA00041197};
DE AltName: Full=Apolipoprotein A4 {ECO:0000256|ARBA:ARBA00042591};
GN Name=APOA4 {ECO:0000313|EMBL:ACC68865.1};
OS Rhinolophus ferrumequinum (Greater horseshoe bat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Rhinolophidae;
OC Rhinolophinae; Rhinolophus.
OX NCBI_TaxID=59479 {ECO:0000313|EMBL:ACC68865.1};
RN [1] {ECO:0000313|EMBL:ACC68865.1}
RP NUCLEOTIDE SEQUENCE.
RA Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA Tsipouri V., Young A., Green E.D.;
RT "NISC Comparative Sequencing Initiative.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the apolipoprotein A1/A4/E family.
CC {ECO:0000256|ARBA:ARBA00008788}.
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DR EMBL; DP000723; ACC68865.1; -; Genomic_DNA.
DR AlphaFoldDB; B2KIF7; -.
DR GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR Gene3D; 1.20.120.20; Apolipoprotein; 2.
DR InterPro; IPR000074; ApoA_E.
DR PANTHER; PTHR18976; APOLIPOPROTEIN; 1.
DR PANTHER; PTHR18976:SF1; APOLIPOPROTEIN A-IV; 1.
DR Pfam; PF01442; Apolipoprotein; 1.
DR SUPFAM; SSF58113; Apolipoprotein A-I; 2.
PE 3: Inferred from homology;
KW HDL {ECO:0000256|ARBA:ARBA00022850};
KW Lipoprotein {ECO:0000313|EMBL:ACC68865.1};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..382
FT /note="Apolipoprotein A-IV"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002778447"
FT REGION 361..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 43560 MW; E12A6ED741333045 CRC64;
MFLKAVVLTL ALVAITGARA EVSADQVATV VWDYFSQLSN NAKEAVEHLQ KSELTQQLNT
LFQDKLGEVN TYAGDLQKKL VPFATDLHER LTKDSEKLKE EIRKELEDLR TRLLPHAEEV
SQKIGDNVRQ LQQRLGPYAD ELRSQVSTQA EQLRRQLTPY AQRMETVLRE NVDNLQTSLT
PYADELKAKI DQNVAELKGR LTPYADELKV KIDQNVEELR RSLAPYAQDV QDKLNHQLDG
LAFQMKKNAE ELKTKISANA EELRQRLVPV AEDVRNKLKG NTEGLQKSLA ELNSHLDQQV
EEFRRKVEPY GETFNKALVQ QVEELKQKLG PHAGDVEGHL SFLEKDLRDK VNSFFSTLKE
KENQDTPLAL PQPEQTQATQ ES
//
