ID   B2TLL0_CLOBB            Unreviewed;       413 AA.
AC   B2TLL0; U4P676;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Sensor histidine kinase {ECO:0000313|EMBL:ACD21923.1};
GN   OrderedLocusNames=CLL_A2107 {ECO:0000313|EMBL:ACD21923.1};
OS   Clostridium botulinum (strain Eklund 17B / Type B).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=935198 {ECO:0000313|EMBL:ACD21923.1, ECO:0000313|Proteomes:UP000001195};
RN   [1] {ECO:0000313|Proteomes:UP000001195}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Eklund 17B / Type B {ECO:0000313|Proteomes:UP000001195};
RA   Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A.,
RA   Smith T.J., Sutton G., Brettin T.S.;
RT   "Complete sequence of Clostridium botulinum strain Eklund.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001056; ACD21923.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2TLL0; -.
DR   KEGG; cbk:CLL_A2107; -.
DR   PATRIC; fig|935198.13.peg.2061; -.
DR   HOGENOM; CLU_038337_0_0_9; -.
DR   Proteomes; UP000001195; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR018771; PocR_dom.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   Pfam; PF10114; PocR; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:ACD21923.1};
KW   Transferase {ECO:0000313|EMBL:ACD21923.1}.
FT   DOMAIN          9..176
FT                   /note="PocR"
FT                   /evidence="ECO:0000259|Pfam:PF10114"
FT   DOMAIN          210..288
FT                   /note="Signal transduction histidine kinase internal
FT                   region"
FT                   /evidence="ECO:0000259|Pfam:PF06580"
FT   DOMAIN          306..411
FT                   /note="Histidine kinase/HSP90-like ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF02518"
SQ   SEQUENCE   413 AA;  47654 MW;  78CF6499EF0F6462 CRC64;
     MEKVLHLKDA IDINAFQKIQ DDISDATEMS IITVDYMGKC ATKHSRCSEF CKLMRASDSY
     SQLCERCDSR GGLEAARLEK PYIYKCHKGL IDFATPIIVD GQYLGSVMAG QVLMEDDEKV
     NLEKIVNSEN NFDSLKKEEK EKLLEAYNKL PVVSFERIQA VAQMMFHISN YIVEEAVSKI
     VQRELDEKKV KFAESEKMQA ELEKEYKASQ LKALQSQINP HFLFNVLNSI SSLSIVENAP
     KTQEVIYNLS NMLRYTLKKA NKIVSLEEEF DYINSYLNLQ KVRFSDRLKY EINIDKQFKN
     IRIPFMVIQT FVENSVVHGL ETKEEGGYIK IFVEDANEYV IVHIEDNGTG IPKEQLNLMK
     EELKIRDDNN LDKIGINNAN KRMAYYYGDE YKIDITSKIR VGTSVKITIK KEV
//