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Database: UniProt
Entry: B2UGE2
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ID   SUCC_RALPJ              Reviewed;         388 AA.
AC   B2UGE2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   14-MAY-2014, entry version 42.
DE   RecName: Full=Succinyl-CoA ligase [ADP-forming] subunit beta;
DE            EC=6.2.1.5;
DE   AltName: Full=Succinyl-CoA synthetase subunit beta;
DE            Short=SCS-beta;
GN   Name=sucC; OrderedLocusNames=Rpic_0474;
OS   Ralstonia pickettii (strain 12J).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=402626;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=12J;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Meincke L., Brettin T.,
RA   Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Marsh T., Richardson P.;
RT   "Complete sequence of chromosome 1 of Ralstonia pickettii 12J.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: ATP + succinate + CoA = ADP + phosphate +
CC       succinyl-CoA.
CC   -!- COFACTOR: Binds 1 magnesium or manganese ion per subunit (By
CC       similarity).
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       succinate from succinyl-CoA (ligase route): step 1/1.
CC   -!- SUBUNIT: Heterotetramer of two alpha and two beta subunits (By
CC       similarity).
CC   -!- SIMILARITY: Belongs to the succinate/malate CoA ligase beta
CC       subunit family.
CC   -!- SIMILARITY: Contains 1 ATP-grasp domain.
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DR   EMBL; CP001068; ACD25629.1; -; Genomic_DNA.
DR   RefSeq; YP_001898061.1; NC_010682.1.
DR   ProteinModelPortal; B2UGE2; -.
DR   SMR; B2UGE2; 1-384.
DR   STRING; 402626.Rpic_0474; -.
DR   EnsemblBacteria; ACD25629; ACD25629; Rpic_0474.
DR   GeneID; 6288968; -.
DR   KEGG; rpi:Rpic_0474; -.
DR   PATRIC; 20251830; VBIRalPic63053_1682.
DR   eggNOG; COG0045; -.
DR   HOGENOM; HOG000007059; -.
DR   KO; K01903; -.
DR   OMA; AAGRICK; -.
DR   OrthoDB; EOG644ZT0; -.
DR   BioCyc; RPIC402626:GH94-475-MONOMER; -.
DR   UniPathway; UPA00223; UER00999.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.30.1490.20; -; 1.
DR   Gene3D; 3.30.470.20; -; 1.
DR   Gene3D; 3.40.50.261; -; 1.
DR   HAMAP; MF_00558; Succ_CoA_beta; 1.
DR   InterPro; IPR011761; ATP-grasp.
DR   InterPro; IPR013650; ATP-grasp_succ-CoA_synth-type.
DR   InterPro; IPR013815; ATP_grasp_subdomain_1.
DR   InterPro; IPR013816; ATP_grasp_subdomain_2.
DR   InterPro; IPR005811; CoA_ligase.
DR   InterPro; IPR017866; Succ-CoA_synthase_bsu_CS.
DR   InterPro; IPR005809; Succ_CoA_synthase_bsu.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   PANTHER; PTHR11815; PTHR11815; 1.
DR   Pfam; PF08442; ATP-grasp_2; 1.
DR   Pfam; PF00549; Ligase_CoA; 1.
DR   PIRSF; PIRSF001554; SucCS_beta; 1.
DR   SUPFAM; SSF52210; SSF52210; 1.
DR   TIGRFAMs; TIGR01016; sucCoAbeta; 1.
DR   PROSITE; PS50975; ATP_GRASP; 1.
DR   PROSITE; PS01217; SUCCINYL_COA_LIG_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Ligase; Magnesium; Manganese;
KW   Metal-binding; Nucleotide-binding; Tricarboxylic acid cycle.
FT   CHAIN         1    388       Succinyl-CoA ligase [ADP-forming] subunit
FT                                beta.
FT                                /FTId=PRO_1000129215.
FT   DOMAIN        9    244       ATP-grasp.
FT   NP_BIND      35    108       ATP (By similarity).
FT   METAL       197    197       Magnesium or manganese (By similarity).
FT   METAL       199    199       Magnesium or manganese (By similarity).
SQ   SEQUENCE   388 AA;  41139 MW;  72CA276E6DEB074B CRC64;
     MNIHEYQGKE ILRKYNVPVP RGIPAFSVDE AIKAAETLGG PVWVVKAQIH AGGRGKGGGV
     KVAKSIEQVK EYASSILGMT LVTHQTGPEG KLVKRLLIEE GADIKKELYV SLVVDRVSQQ
     VALMASSEGG MDIEEVAESH PEKIHTLLID PQAGLQDAQA DDIARKIGVP DASVPQARQA
     LQGLYKAFWE TDASQAEINP LILTGDGKVI ALDAKFNFDS NALFRHPEIV AYRDLDEEDP
     AEIEASKFDL AYISLDGNIG CLVNGAGLAM ATMDTIKLFG GEPANFLDVG GGATTEKVTE
     AFKLMLKNPD VKAILVNIFG GIMRCDVIAE GVIAAAKAVS LSVPLVVRMK GTNEDLGKKM
     LADSGLPIIA ADTMAEAAEK VVAAAAGK
//
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