ID   B2UQY0_AKKM8            Unreviewed;      1865 AA.
AC   B2UQY0;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Outer membrane autotransporter barrel domain protein {ECO:0000313|EMBL:ACD04865.1};
GN   OrderedLocusNames=Amuc_1039 {ECO:0000313|EMBL:ACD04865.1};
OS   Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS   81048 / CCUG 64013 / CIP 107961 / Muc).
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC   Akkermansiaceae; Akkermansia.
OX   NCBI_TaxID=349741 {ECO:0000313|EMBL:ACD04865.1, ECO:0000313|Proteomes:UP000001031};
RN   [1] {ECO:0000313|Proteomes:UP000001031}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013
RC   / CIP 107961 / Muc {ECO:0000313|Proteomes:UP000001031};
RX   PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA   van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA   Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT   "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT   degrader, and its use in exploring intestinal metagenomes.";
RL   PLoS ONE 6:E16876-E16876(2011).
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DR   EMBL; CP001071; ACD04865.1; -; Genomic_DNA.
DR   RefSeq; WP_012420080.1; NZ_CP071807.1.
DR   PaxDb; 349741-Amuc_1039; -.
DR   KEGG; amu:Amuc_1039; -.
DR   eggNOG; COG4625; Bacteria.
DR   HOGENOM; CLU_234731_0_0_0; -.
DR   BioCyc; AMUC349741:G1GBX-1110-MONOMER; -.
DR   Proteomes; UP000001031; Chromosome.
DR   Gene3D; 2.40.128.130; Autotransporter beta-domain; 1.
DR   InterPro; IPR005546; Autotransporte_beta.
DR   InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR   Pfam; PF03797; Autotransporter; 1.
DR   SMART; SM00869; Autotransporter; 1.
DR   SUPFAM; SSF103515; Autotransporter; 1.
DR   PROSITE; PS51208; AUTOTRANSPORTER; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001031};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..1865
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002781319"
FT   DOMAIN          1580..1865
FT                   /note="Autotransporter"
FT                   /evidence="ECO:0000259|PROSITE:PS51208"
SQ   SEQUENCE   1865 AA;  188661 MW;  8C2E987E96D5437E CRC64;
     MRLHLPITLL AAVLACYTSV SLAVPTSESP AWGADSTFNN NEPANEYSVT GSQSVNLDVN
     SGNNNYSTGL YIGAGSSFTI NQNANGGCTI NLNGAFAGEG NLTLVAANGN AGYASKFVLG
     SQESSFSGNI ILSQKGTQPG GAILQITGTA LANATVDLSG SINQSSSALT LQISNAASLA
     GLNDADGFSG THKGRVQSAN SSRANLTLTG NGNYTYGGSI GATTQHSGVN GNTTPTGGIN
     LIMAGTGTQN LTGTVINANI TAQGGILKIN NSSLAYSGII TMAGGTLDFT SATLGANAVL
     NMNGTGVLKN AAIDGAKLTY TESGSSFTKE NVTFTSGTID IGGALDSLVE GEQGYTFDLG
     SNLGANFTVT GLDTGQYRIE GSVLTIEDGA ISSVTWVSAG EGGELEETVK NAFTLALGEG
     SAANVSLGYL NGTLTTSGDK VYQITNTGGT KINLSGVYNS GATLPSGNLN YQGDIWMDIN
     GGAFGIIAGG VTNEWGTNLQ TSTLTGDTHV QLSGNATAEH VIGGNNKGAS TTLTGNTNVT
     VKDNAIVAGA IIGGSTSSHN AVTTITGNTS VLVTNIQHSN SATVNLGDFG NVTAQNFITG
     GSAWTANQTS GTTIQGNTSV TINVGDAELS GTEGHNNFVK NIYGGSYANT KSEGNGAVQK
     VEGNSSVSIS GKEGITFTGD IMGGSFWNWG NGTTLTTNGN TSVSIDGGST FTGKIVGGSW
     RGSTWTAEDP TALPVSIGGN ITVTLGQGTY LGDIYGAGNC GTVGGEVHVS LTGGSIFGEE
     GEESGITIGG SAGAAVEGNR TLELKGTFGT GDFQNVTFTR FDEINIAQEE TSATIYALTD
     SPALTKTGAG TLTLGADAAG AETILDGTTE GITISEGSLN LSGAGGSHMK GTWNIASGSR
     LTGVSGTVTV GEGGLDGLTI ALGTENIGQD TQASGAVIIN GSGTGSDPNL SIEGEGLTLD
     LSNDAVVNLL LDHKTDDSSS YLTLTSGTLT VGDLGDIAFT TDLLSNYGIR VTGTDGGSLV
     LSGAATGLYR VQEEGGNAHE VNSYQTLSGY AGVVIGGGQT LTVNLAGAPG ESDGQGAKIN
     NLMGATGSSL VVNNTGDGTA VVILNNKQMT TGEDDIDPAG QDTVMGGSIT GGNNVAFIKE
     GTGTLTVGGT MDVETLALRE GNIVLNGASN TLDTLTLEGG GLTINGNAEV GTITGTEAGG
     SLTIQGTLNL TGTGEINDGS ITGTGTLRIQ EGAELALGGE ARLDGTSVTA DGTLALSGTE
     SGAIISLSGS GTLSMNGGSL SISSATTSSG TFSGTLAGSG TLDISGQATQ YLQTGNKDYD
     LAVRDGGVLV LKGTADAPTL NYNSITAGNN GTLRIEATGD AQGSANTTLN VESITFQNGS
     TTELIYNFNQ DAPFGAPMLT ADTITVQDGA GFLLSNMEGN AAMNAGSDLH DVILMSATGS
     ISGLEDGQSL AARISGLFAV YYQDATLNRD GNDILLNATL RQENLFASAA DTWNSAAGAS
     LLWEARKNLD PDSQLAQFMN GVSTMINDGN LSGATRAMAA AAGSTVNALG TAQRDALRDQ
     MGWIRNRTTL MGVNPAYVND DLPRFHMWME GTGSYAKLDT RGDESGYQLT TWGGTVGVDA
     DLSDRLTVGA AFTASYGDLT AGAADSADGH LDSYYASLFG RYQDRRWAHT LILTGGWNDA
     KLNRTVNYGE GSYGTQGSTS GWGFGAMYEL TYDVYLNENR SSVLQPLFNA SVVTTRMDGY
     EETGAGNAGL NVGRQDWTTG TLALGGRWMG LVGSNIFGRE ALAEIRVNAA QDLGDRRGET
     NVSLLGNPGF AQSVRGAKVG TTALQLGAGL SVPVGTKGTI YVNGNADIRD GSSALNGSIG
     YRHDF
//