ID B2URI0_AKKM8 Unreviewed; 795 AA.
AC B2URI0;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Tetratricopeptide TPR_2 repeat protein {ECO:0000313|EMBL:ACD05065.1};
GN OrderedLocusNames=Amuc_1240 {ECO:0000313|EMBL:ACD05065.1};
OS Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS 81048 / CCUG 64013 / CIP 107961 / Muc).
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Akkermansiaceae; Akkermansia.
OX NCBI_TaxID=349741 {ECO:0000313|EMBL:ACD05065.1, ECO:0000313|Proteomes:UP000001031};
RN [1] {ECO:0000313|Proteomes:UP000001031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013
RC / CIP 107961 / Muc {ECO:0000313|Proteomes:UP000001031};
RX PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT degrader, and its use in exploring intestinal metagenomes.";
RL PLoS ONE 6:E16876-E16876(2011).
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DR EMBL; CP001071; ACD05065.1; -; Genomic_DNA.
DR AlphaFoldDB; B2URI0; -.
DR STRING; 349741.Amuc_1240; -.
DR PaxDb; 349741-Amuc_1240; -.
DR KEGG; amu:Amuc_1240; -.
DR eggNOG; COG0457; Bacteria.
DR eggNOG; COG1729; Bacteria.
DR HOGENOM; CLU_353264_0_0_0; -.
DR Proteomes; UP000001031; Chromosome.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 6.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR Pfam; PF13432; TPR_16; 4.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF48452; TPR-like; 4.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001031};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 526..559
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 795 AA; 88789 MW; D81FF71794D69DA7 CRC64;
MFSAAQENIP DAAPIADGPL VANPEQDTLD MADMLYKQAQ APATKENRQE YGRLLDLSLR
KYLEFTQRFP QSAQAPLAEY RAAMCLEELG RKDEAHGLFL RLIQTGSPAL VAASAYRLAT
DASSAGEIDK AIQYYQLVIR NAEQNDLKVD AQYRLGRLFL SSGNPEAAAT MFCAVMGNPE
ADAKFVLVSR MGYAALCADT GRLGEAYSEY RKVLETPGVD NRNRGIATLQ AAMLATKLKK
TAEAQGLYER LLKDESLKEM APEARMGLLL GLYNMGKYRE ILSQYEQQKG IKMPTKDGQV
RLLMLLGQSA YKLKEYRKAA DFFLEAEKSV PYTQEAMQAS FYRLLCYNEL KQKDLPQRAQ
SFLNHYAKAF PTSELHDMVR LMAAENLFSS NPADAARFYA SIDFDKVPPK MRADILYKSA
WAIAQAGNRG VAAKLLTDFI NDFPKDPRIC EALTLRGDMY AKTKKEAEAL MDFDRVIARW
PKAESAAAAW QRAAQIYAGR QDMANMAKYY EGLIQNFPKA SPAALAEAHF LLGRAAFDQG
DFKSSISHMA EAKTLDPQKY GEQVNVLSVL SYHKLQDVNK LKEALETLQK ENPSAVARVP
DVIPAWLGLQ AYGMKDLETA DKYMTWATQN DQLQNVKKVI WRNLAKVRLA LRKYDRALVA
SNNFLKDEDQ PYRRADGMLD KASILLGLGK YADARKTAED ALALGVEGPL MASLKIVLGD
ISYAEKKFDE AAKHYGVTAE LFVNDAELKP KALFKAAEAL DKAGRKSEAS QYRARLQKEF
PDWKQDGESL PPDAR
//
