ID B2VJB4_ERWT9 Unreviewed; 696 AA.
AC B2VJB4;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:CAO96519.1};
GN OrderedLocusNames=ETA_14730 {ECO:0000313|EMBL:CAO96519.1};
OS Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB
OS 4357 / Et1/99).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=465817 {ECO:0000313|EMBL:CAO96519.1, ECO:0000313|Proteomes:UP000001726};
RN [1] {ECO:0000313|EMBL:CAO96519.1, ECO:0000313|Proteomes:UP000001726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99
RC {ECO:0000313|Proteomes:UP000001726};
RX PubMed=18462403; DOI=10.1111/j.1462-2920.2008.01639.x;
RA Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R.,
RA Geider K.;
RT "The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic
RT bacterium in the genus Erwinia.";
RL Environ. Microbiol. 10:2211-2222(2008).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CU468135; CAO96519.1; -; Genomic_DNA.
DR RefSeq; WP_012441213.1; NC_010694.1.
DR AlphaFoldDB; B2VJB4; -.
DR STRING; 465817.ETA_14730; -.
DR KEGG; eta:ETA_14730; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_6; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000001726; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:CAO96519.1};
KW Cilium {ECO:0000313|EMBL:CAO96519.1};
KW Flagellum {ECO:0000313|EMBL:CAO96519.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000001726};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 46..65
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 117..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 209..231
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 251..273
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 696 AA; 74858 MW; DC43E0CC784193B9 CRC64;
MANLAALLRL PGSMKETQWK VLAGPVLILL ILSMMVLPLP PFILDLLFTF NIALSIMVLL
VAMFTQRTLD FAAFPTILLF STLLRLALNV ASTRVILMDG HTGAGAAGRV VEAFGHFLVG
GNFAIGIVVF IILVIINFMV ITKGAGRIAE VGARFVLDGM PGKQMAIDAD LNAGLIGEEE
AKKRRSDVTQ EADFYGSMDG ASKFVRGDAI AGIMIMVINV IGGLLVGVIQ HGMDAGHAAE
TYTLLTIGDG LVAQIPALVI STAAGVIVTR VGTDQDVGEQ MVGQMFNNPR VMMLSAGVLG
MLGLVPGMPN FVFLLFTAGL LGLAWWVRGK QMTPQAPAVA QSSSMQPENS GSMEATWGDV
QLEDSLGMEV GYRLIPMVDS AQDGELLGRI RSIRKKFAQE MGFLPPVVHI RDNMDLTPAR
YRILMKGVEI GSGDAFPGRW MAINPGTAAG TLPGEKTTDP AFGLEAIWID SALKEQAQIQ
GFTVVEASTV VATHLNHLIG QYASELFGRQ EAQQLLDRVT QEMPKLTEDL IPGVITLTTL
HKVLQNLLSE RVSIRDMRTI IETLAEHAAV QTDPHELTSV VRVALGRAIT QQWFPGAGEV
QVIGLDTTLE RLLLQALQGG GGLEPGLADR LLTQAQSALQ HQEGLGAPPV LLVNHPLRAL
LARFLRRSLP QLIVISNMEL TDNRQIRMTS TIGSQS
//
