ID   B2ZXX4_9CAUD            Unreviewed;       472 AA.
AC   B2ZXX4;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   24-JAN-2024, entry version 56.
DE   RecName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000256|ARBA:ARBA00035036};
DE            EC=2.4.2.12 {ECO:0000256|ARBA:ARBA00035024};
GN   Name=pncB {ECO:0000313|EMBL:BAG41550.1};
OS   Ralstonia phage phiRSL1.
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Mieseafarmvirus; Mieseafarmvirus RSL1.
OX   NCBI_TaxID=1980924 {ECO:0000313|EMBL:BAG41550.1, ECO:0000313|Proteomes:UP000001034};
RN   [1] {ECO:0000313|EMBL:BAG41550.1, ECO:0000313|Proteomes:UP000001034}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=20034649; DOI=10.1016/j.virol.2009.11.043;
RA   Yamada T., Satoh S., Ishikawa H., Fujiwara A., Kawasaki T., Fujie M.,
RA   Ogata H.;
RT   "A jumbo phage infecting the phytopathogen Ralstonia solanacearum defines a
RT   new lineage of the Myoviridae family.";
RL   Virology 398:135-147(2010).
CC   -!- PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-
CC       ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and
CC       nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00035007}.
CC   -!- SIMILARITY: Belongs to the NAPRTase family.
CC       {ECO:0000256|ARBA:ARBA00010897}.
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DR   EMBL; AB366653; BAG41550.1; -; Genomic_DNA.
DR   OrthoDB; 5829at10239; -.
DR   Proteomes; UP000001034; Genome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR041529; DUF5598.
DR   InterPro; IPR041525; N/Namide_PRibTrfase.
DR   InterPro; IPR016471; Nicotinamide_PRibTrfase.
DR   InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR   PANTHER; PTHR43816; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR43816:SF1; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; 1.
DR   Pfam; PF18127; NAMPT_N; 1.
DR   Pfam; PF04095; NAPRTase; 1.
DR   PIRSF; PIRSF005943; NMPRT; 1.
DR   SUPFAM; SSF51690; Nicotinate/Quinolinate PRTase C-terminal domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW   ECO:0000313|EMBL:BAG41550.1};
KW   Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001034};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:BAG41550.1}.
FT   DOMAIN          9..103
FT                   /note="Nicotinamide phosphoribosyltransferase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18127"
FT   DOMAIN          177..421
FT                   /note="Nicotinate/nicotinamide phosphoribosyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04095"
SQ   SEQUENCE   472 AA;  52138 MW;  997A8198BF6C0064 CRC64;
     MQEQINDFNF AADTDSYKYS HGPQVPKSLA YVSSYGEARS DAVFRGALFS GMQVRVKDML
     EKPLTMADVD FAYEMAMAHC GTFPLEMMKK IVTQYGGLPP VRIQALPEGL VVPNRTALWQ
     IANLDPSMPT LPQFMEDQIL RDVWYMSTVA TLSWHIKQDI LAFLNRTCDN PEEEIVFRLH
     DFGARGASSR ETAAHGGLAH LINFMGTDTV LALYAARRYY GEKVAGFSIP AMEHFTVTAW
     GRENEAQAYA NMVDTFGGEG RIYACVSDAY DIFNAVDNIW GQQLKDRVLA KGGRLVVRPD
     SGDPTSVVLY CVKSLARSFG TTTNKKGFQV LHPAVRVIQG DGVNRESIRS ILTALEINGF
     SAENVAFGMG GALLQGVNRD TLGFAQKASA ITSGHSRWIG ISKEPVTAKQ KVSKKGRLAV
     VRESDSYLTI QESELGGREN LLQDVFDGQS LVRDMSFSEV RENANRSVLP RL
//