ID   B3C7E7_9BACE            Unreviewed;       988 AA.
AC   B3C7E7;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Peptidase M16 inactive domain protein {ECO:0000313|EMBL:EDV07271.1};
DE            EC=3.4.24.- {ECO:0000313|EMBL:EDV07271.1};
GN   ORFNames=BACINT_00838 {ECO:0000313|EMBL:EDV07271.1};
OS   Bacteroides intestinalis DSM 17393.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=471870 {ECO:0000313|EMBL:EDV07271.1, ECO:0000313|Proteomes:UP000004596};
RN   [1] {ECO:0000313|EMBL:EDV07271.1, ECO:0000313|Proteomes:UP000004596}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17393 {ECO:0000313|EMBL:EDV07271.1,
RC   ECO:0000313|Proteomes:UP000004596};
RA   Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA   Gordon J.;
RT   "Draft genome sequence of Bacteroides intestinalis (DSM 17393).";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EDV07271.1, ECO:0000313|Proteomes:UP000004596}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17393 {ECO:0000313|EMBL:EDV07271.1,
RC   ECO:0000313|Proteomes:UP000004596};
RA   Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA   Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EDV07271.1}.
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DR   EMBL; ABJL02000006; EDV07271.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3C7E7; -.
DR   STRING; 471870.BACINT_00838; -.
DR   eggNOG; COG0612; Bacteria.
DR   Proteomes; UP000004596; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EDV07271.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   TRANSMEM        20..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          71..115
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          271..443
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          739..893
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   988 AA;  112546 MW;  D60B6CC2703D35C1 CRC64;
     MKKTHIFAVI NLISQLMNKL FRQIGLMLIL LVAISLGSCT SKYSYETVPN DPLKARIYTL
     DNGLKVYMTV NKETPRIQTY IAVRVGGKND PAETTGLAHY FEHLMFKGTT NFGTQNYEIE
     KPLLDQIEAQ FEIYRKTTDS LERKAIYAKI DSISYEASKY AIPNEYDKLM AAIGANGTNA
     YTSFDVTCYT EDIPSNQIDN WAKIQAERFE NCVIRGFHTE LETVYEEKNM SLTRDPRKVY
     EAVLSSLFPH HPYGTQTVLG TQEDLKNPSI TNIKEYYKKW YVPNNMAICL SGDFDPDQMI
     ATIDKYFGGL KPNPDLPKLD LPKETPITAP VVREILGPDA ESVALAWRFP GAADKDVETL
     QVVSQILYNG QAGLIDLDLT QQQKTLSAYC YPMTMSDYSA FMMQGRPKQG QTLDEVKDLL
     LGELKKLREG DFDEKMLEAN INNFKLYQMQ QLENNDARAD MFVESFVNGS DWADEVTALD
     RMSKLTKDDI VAFANKYLKD DNYAVIYKKQ GKDPNEKKMS KPEITPIVMN RDTVSTFLKE
     IQASVVTPIE PVFLDYSKDL TQLKAKSDIP VLYKQNTTND IFQLIYLFDM GNNNDKALGT
     AAQYLEYLGT ADMTPEEVKS EFYRLACSFF VSPGTKRTYV VLSGLSENMP AAMALFEKLM
     ANAKVNPEAY TNMANDILKS RKDAKLNQMQ NFSRLVTYAT YGPKSPSTNI LTEAELTSMD
     PQQLVDRIKQ LNSFKHRILY YGPNNQDELL AIINKEHQAP ETLNEIPEGN NFEPLLTPET
     KIFIAPYEAK QIYMSQVSNK GEKFDPAAES GRQLYNEYFG GGMNSIVFQE MRESRGLAYS
     AWAGMLRPSY LTDPYTLRTQ IATQNDKMID AINTFNDIIN NMPESEAAFK LAKDGMIARM
     RTDRTIKMDV IWDYISAQYL GQNVDSRIKL YNDVQNMTLQ DVIDYQNKWI KGRTYTYCIL
     GDKKELDMES LKKVGPVIEL KQEDIFGY
//