ID   B3DKJ3_DANRE            Unreviewed;       662 AA.
AC   B3DKJ3;
DT   22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2008, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   SubName: Full=Snx1 protein {ECO:0000313|EMBL:AAI63869.1};
GN   Name=snx1a {ECO:0000313|ZFIN:ZDB-GENE-060302-3};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI63869.1};
RN   [1] {ECO:0000313|EMBL:AAI63869.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004287};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004287};
CC       Cytoplasmic side {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   EMBL; BC163869; AAI63869.1; -; mRNA.
DR   RefSeq; NP_001122143.2; NM_001128671.2.
DR   AlphaFoldDB; B3DKJ3; -.
DR   GeneID; 337386; -.
DR   KEGG; dre:337386; -.
DR   AGR; ZFIN:ZDB-GENE-060302-3; -.
DR   CTD; 337386; -.
DR   ZFIN; ZDB-GENE-060302-3; snx1a.
DR   OrthoDB; 1891044at2759; -.
DR   PhylomeDB; B3DKJ3; -.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0010008; C:endosome membrane; IBA:GO_Central.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR   GO; GO:0034498; P:early endosome to Golgi transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd07665; BAR_SNX1; 1.
DR   CDD; cd07281; PX_SNX1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR034901; PX_SNX1.
DR   InterPro; IPR028660; SNX1_BAR.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR10555; SORTING NEXIN; 1.
DR   PANTHER; PTHR10555:SF129; SORTING NEXIN-1; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          283..412
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          1..172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          185..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          586..613
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        30..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..137
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..223
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        254..268
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   662 AA;  74407 MW;  0C5CFAFFEF28F97A CRC64;
     MAASSERSPP PFPDSEEPEL LEDSDEGADA FTGTSISEMD SPSPDTTGHS KDIFSDPAED
     IFSDPLSDIN SEPKKNSDVK IPSPASDEAV DLFSDPLDDD EPSEMSSPEV QNPVPDLSNE
     PAEPPKSDNK KPIFEPAAKV KKAASSELFD DDEDDEDLFQ ESFKPVMKKP QASVPPLDVY
     TEVKVKPQVK DDPTDLFTEE ALTPPASKPA ANTRTNGVHS EEQDLFSEAT VELSLDSPHN
     DRKKKDSVNP SVSAPAAPVA SSSSKPPSKT LEELEEEESE DKFDLNVSIT NPEKVGDGMN
     AYMVYKVSTQ TSLSMFRSKT FTVRRRFSDF LGLYEKLSEK HSQNGYIVPP PPEKSIMGMT
     KVKVGKEDPS SAEFVERRRA ALERYLQRVV SHPSLLQDPD VREFLEKEEL PRAVSTQTLS
     GAGFLKMLNK ATDAVSKMTI KMNEQDVWFD EKIQDVENEE QLLRKLHVMV ESLVNHRKEL
     SGNTAAFAKS VAMLGSSEDN TALSRALSQL AEVEDRIEQL HRDQAANDFF TFAELLADYI
     RLLGAVRGCF DQRMKAWQRW QDAESMLQKK REAEAKLLWA NKPDKLQQAK DEIAEWEAKV
     TQYERDFERI SATVQKDVIR FDKEKARDFK RQIIKYLESL LHSQQQLIKY WEAFLPEAKA
     IA
//