ID B3E057_METI4 Unreviewed; 325 AA.
AC B3E057;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Arabinose 5-phosphate isomerase and CBS domains {ECO:0000313|EMBL:ACD82718.1};
GN Name=gutQ {ECO:0000313|EMBL:ACD82718.1};
GN OrderedLocusNames=Minf_0663 {ECO:0000313|EMBL:ACD82718.1};
OS Methylacidiphilum infernorum (isolate V4) (Methylokorus infernorum (strain
OS V4)).
OC Bacteria; Verrucomicrobiota; Methylacidiphilae; Methylacidiphilales;
OC Methylacidiphilaceae; Methylacidiphilum (ex Ratnadevi et al. 2023).
OX NCBI_TaxID=481448 {ECO:0000313|EMBL:ACD82718.1, ECO:0000313|Proteomes:UP000009149};
RN [1] {ECO:0000313|EMBL:ACD82718.1, ECO:0000313|Proteomes:UP000009149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate V4 {ECO:0000313|Proteomes:UP000009149};
RX PubMed=18593465; DOI=10.1186/1745-6150-3-26;
RA Hou S., Makarova K.S., Saw J.H., Senin P., Ly B.V., Zhou Z., Ren Y.,
RA Wang J., Galperin M.Y., Omelchenko M.V., Wolf Y.I., Yutin N., Koonin E.V.,
RA Stott M.B., Mountain B.W., Crowe M.A., Smirnova A.V., Dunfield P.F.,
RA Feng L., Wang L., Alam M.;
RT "Complete genome sequence of the extremely acidophilic methanotroph isolate
RT V4, Methylacidiphilum infernorum, a representative of the bacterial phylum
RT Verrucomicrobia.";
RL Biol. Direct 3:26-26(2008).
CC -!- SIMILARITY: Belongs to the SIS family. GutQ/KpsF subfamily.
CC {ECO:0000256|ARBA:ARBA00008165, ECO:0000256|PIRNR:PIRNR004692}.
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DR EMBL; CP000975; ACD82718.1; -; Genomic_DNA.
DR RefSeq; WP_012463000.1; NC_010794.1.
DR AlphaFoldDB; B3E057; -.
DR STRING; 481448.Minf_0663; -.
DR KEGG; min:Minf_0663; -.
DR eggNOG; COG0517; Bacteria.
DR eggNOG; COG0794; Bacteria.
DR HOGENOM; CLU_040681_13_1_0; -.
DR OrthoDB; 9762536at2; -.
DR Proteomes; UP000009149; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05014; SIS_Kpsf; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR004800; KdsD/KpsF-type.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR035474; SIS_Kpsf.
DR NCBIfam; TIGR00393; kpsF; 1.
DR PANTHER; PTHR42745; -; 1.
DR PANTHER; PTHR42745:SF1; ARABINOSE 5-PHOSPHATE ISOMERASE KDSD; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01380; SIS; 1.
DR PIRSF; PIRSF004692; KdsD_KpsF; 1.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Isomerase {ECO:0000313|EMBL:ACD82718.1}.
FT DOMAIN 38..180
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 206..264
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 273..325
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT SITE 55
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
FT SITE 107
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
FT SITE 148
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
FT SITE 189
FT /note="Catalytically relevant"
FT /evidence="ECO:0000256|PIRSR:PIRSR004692-3"
SQ SEQUENCE 325 AA; 35483 MW; 49C72413F8667431 CRC64;
MQEDLVGLAK RVFDLEMDAL RIVRKQLNAA FEQAILVLEK TILANGKIVV TGVGKSGHIG
RKIAATLTST GAPSVVLDAV NAFHGDLGMV NRGDAVVALS YSGETEEILR LVPHLKRMTT
SLIAITGNEN STLAKNSDLV LSVRIDREAC PLNLAPTSST TAMLVLGDAL AMVLLEKRGF
KKEDFARFHP GGTLGRNLLL KVGDIMRPLS QIVILEEEAK VKEALRLWNV KRVGAVVVVN
PGGKVIGIFT HGDFVRNYEV NHRIGEEPLG KVMTKNPVTV RVDKLAVEVL NVFEHNKIED
LIVVDEQYRV VGLIDSQDLA IHRLL
//
