ID B3F907_9BACT Unreviewed; 348 AA.
AC B3F907;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=citrate synthase (unknown stereospecificity) {ECO:0000256|ARBA:ARBA00012972};
DE EC=2.3.3.16 {ECO:0000256|ARBA:ARBA00012972};
DE Flags: Fragment;
GN Name=aclA {ECO:0000313|EMBL:ABV48801.1};
OS enrichment culture clone BSaclA39.
OC Bacteria; environmental samples.
OX NCBI_TaxID=470974 {ECO:0000313|EMBL:ABV48801.1};
RN [1] {ECO:0000313|EMBL:ABV48801.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18523725; DOI=10.1007/s00792-008-0167-5;
RA Voordeckers J.W., Do M.H., Hugler M., Ko V., Sievert S.M., Vetriani C.;
RT "Culture dependent and independent analyses of 16S rRNA and ATP citrate
RT lyase genes: a comparison of microbial communities from different black
RT smoker chimneys on the Mid-Atlantic Ridge.";
RL Extremophiles 12:627-640(2008).
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
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DR EMBL; EF644668; ABV48801.1; -; Genomic_DNA.
DR AlphaFoldDB; B3F907; -.
DR UniPathway; UPA00223; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046912; F:acyltransferase activity, acyl groups converted into alkyl on transfer; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR CDD; cd06100; CCL_ACL-C; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR InterPro; IPR005811; SUCC_ACL_C.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR23118; ATP-CITRATE SYNTHASE; 1.
DR PANTHER; PTHR23118:SF42; ATP-CITRATE SYNTHASE; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR Pfam; PF00549; Ligase_CoA; 1.
DR PRINTS; PR01798; SCOASYNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Lyase {ECO:0000313|EMBL:ABV48801.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..101
FT /note="ATP-citrate synthase/succinyl-CoA ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00549"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABV48801.1"
FT NON_TER 348
FT /evidence="ECO:0000313|EMBL:ABV48801.1"
SQ SEQUENCE 348 AA; 38226 MW; 333AAF35ACE6C754 CRC64;
CIAIGGDRFP GSDFLDHMLR FEKNPQVKMM VLLGEVGGEL EYRVAEAIKD GRITKPVIAW
CIGTISKHFG GEVQFGHAGA KAGAERETAD AKNEALREAG AYVPKSFNDL PELIRGVYEE
LHAKGEIPEI KEPEVPPIPE DYAKALKEGK VRKPTNFICT ISDDRGEEAT YCGVPISEVV
EKGYSIADVI GLLWFKKKFP EWASNFIDMV IRVVADHGPA VSGAHNTKVT ARAGKDLMSS
IVTGILTIGP RFGGAIDGAA KYFKMAKEKG MDPYEFVDYM KNVEKIPIPG IGHRIKSIKN
PDKRVELLKN YAKNNFPSTD LLDYALEVEK VTTSKKENLI LNVDGSIG
//
