ID B3GLN6_9CALI Unreviewed; 106 AA.
AC B3GLN6;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 08-NOV-2023, entry version 43.
DE SubName: Full=Non-structural polyprotein {ECO:0000313|EMBL:ACD91872.1};
DE Flags: Fragment;
OS Norovirus Hu/GII/Beijing/277/2005/CHN.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
OX NCBI_TaxID=535539 {ECO:0000313|EMBL:ACD91872.1};
RN [1] {ECO:0000313|EMBL:ACD91872.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Hu/GII/Beijing/277/2005/CHN {ECO:0000313|EMBL:ACD91872.1};
RX PubMed=19062336; DOI=10.1016/j.jcv.2008.10.002;
RA Guo L., Song J., Xu X., Ren L., Li J., Zhou H., Wang M., Qu J., Wang J.,
RA Hung T.;
RT "Genetic analysis of norovirus in children affected with acute
RT gastroenteritis in Beijing, 2004-2007.";
RL J. Clin. Virol. 44:94-98(2009).
CC -!- FUNCTION: Viral genome-linked protein is covalently linked to the 5'-
CC end of the positive-strand, negative-strand genomic RNAs and subgenomic
CC RNA. Acts as a genome-linked replication primer. May recruit ribosome
CC to viral RNA thereby promoting viral proteins translation.
CC {ECO:0000256|ARBA:ARBA00025359}.
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DR EMBL; EU703669; ACD91872.1; -; Genomic_RNA.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0039694; P:viral RNA genome replication; IEA:InterPro.
DR Gene3D; 3.30.70.270; -; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR InterPro; IPR007094; RNA-dir_pol_PSvirus.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50507; RDRP_SSRNA_POS; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT DOMAIN 1..106
FT /note="RdRp catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50507"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACD91872.1"
FT NON_TER 106
FT /evidence="ECO:0000313|EMBL:ACD91872.1"
SQ SEQUENCE 106 AA; 11606 MW; 38DDCDA4BB318B7D CRC64;
DYSRWDSTQQ RAVLAAALEI MVKFSPEPHL AQKVAEDLLS PSVMDVGDFK ISINEGLPSG
VPCTSQWNSI AHWLLTLCAL SEVTNLSPDI IQANSLFSFD GDDEIV
//
