ID B3GWD5_CAEEL Unreviewed; 448 AA.
AC B3GWD5;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE SubName: Full=Choline/ethanolamine kinase {ECO:0000313|EMBL:CAQ58098.1};
GN Name=cka-1 {ECO:0000313|EMBL:CAQ58098.1,
GN ECO:0000313|WormBase:C28D4.2b};
GN ORFNames=C28D4.2 {ECO:0000313|WormBase:C28D4.2b}, CELE_C28D4.2
GN {ECO:0000313|EMBL:CAQ58098.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAQ58098.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAQ58098.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAQ58098.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; BX284604; CAQ58098.1; -; Genomic_DNA.
DR RefSeq; NP_001129849.1; NM_001136377.2.
DR AlphaFoldDB; B3GWD5; -.
DR SMR; B3GWD5; -.
DR EPD; B3GWD5; -.
DR PeptideAtlas; B3GWD5; -.
DR EnsemblMetazoa; C28D4.2b.1; C28D4.2b.1; WBGene00000509.
DR GeneID; 177807; -.
DR AGR; WB:WBGene00000509; -.
DR WormBase; C28D4.2b; CE08431; WBGene00000509; cka-1.
DR HOGENOM; CLU_012712_2_0_1; -.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00000509; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; B3GWD5; baseline and differential.
DR GO; GO:0005938; C:cell cortex; IDA:WormBase.
DR GO; GO:0005737; C:cytoplasm; IDA:WormBase.
DR GO; GO:0004103; F:choline kinase activity; IDA:WormBase.
DR GO; GO:0004305; F:ethanolamine kinase activity; IBA:GO_Central.
DR GO; GO:0006657; P:CDP-choline pathway; IDA:WormBase.
DR GO; GO:0006646; P:phosphatidylethanolamine biosynthetic process; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05156; ChoK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603:SF104; CHOLINE KINASE A; 1.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 1: Evidence at protein level;
KW Kinase {ECO:0000313|EMBL:CAQ58098.1};
KW Proteomics identification {ECO:0007829|EPD:B3GWD5,
KW ECO:0007829|PeptideAtlas:B3GWD5};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transferase {ECO:0000313|EMBL:CAQ58098.1}.
SQ SEQUENCE 448 AA; 51407 MW; 41968E760EDE4F77 CRC64;
MVSLEVPTES PCISRRAPSE ECEIAFSHDD PTLMWKDRTT DCVDLKKVFS KFDSSAPISG
EILFRARFLC AKYLGGAWRK VKIEEFRIRA ITGGMSNLLF LVELPAHLTP IQMEPEKALL
RVHCQSDIDQ LLSESVVFTL LSERNLGPKM LGVFPGGRFE QFIPSRALQC LEISKPGLSK
LIAPIVARVH TLDAPIPKEP QTLQTARQWL ERFKKTPAGE RPIEMYLTQA KVPKSDYPST
ITVAQLEREL NFVEFFLQHS HSPVVFSHND LQEGNFLLID GYKLADDGTV LTPDGKPTND
DPLSLIDFEY CSYNYRGFDL GNHFCEYGYD YNEAEAPYYK IHQHYFEVEK ERKVFCEAYL
DEVYKMRACG DNPHFPSDLV TGDREKDLNK IIEESILFMP VSNIFWVCWS LINAEESSIA
FDYGAYGRDR LALYFHQKKN LEKYLSNL
//
