ID   B3LKD9_YEAS1            Unreviewed;       347 AA.
AC   B3LKD9;
DT   02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   02-SEP-2008, sequence version 1.
DT   24-JAN-2024, entry version 57.
DE   RecName: Full=THIF-type NAD/FAD binding fold domain-containing protein {ECO:0000259|Pfam:PF00899};
GN   ORFNames=SCRG_02653 {ECO:0000313|EMBL:EDV11367.1};
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006 {ECO:0000313|EMBL:EDV11367.1, ECO:0000313|Proteomes:UP000008335};
RN   [1] {ECO:0000313|Proteomes:UP000008335}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a {ECO:0000313|Proteomes:UP000008335};
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CH408046; EDV11367.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3LKD9; -.
DR   SMR; B3LKD9; -.
DR   HOGENOM; CLU_002556_4_1_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   CDD; cd01492; Aos1_SUMO; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR10953:SF162; SUMO-ACTIVATING ENZYME SUBUNIT 1; 1.
DR   PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE   4: Predicted;
FT   DOMAIN          16..343
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   347 AA;  39273 MW;  1ADB7B817BA27F3E CRC64;
     MDMKVEKLSE DEIALYDRQI RLWGMTAQAN MRSAKVLLIN LGAIGSEITK SIVLSGIGHL
     TILDGHMVTE EDLGSQFFIG SEDVGQWKID ATKERIQDLN PRIELNFDKQ DLQEKDEEFF
     QQFDLVVATE MQIDEAIKIN TLTRKLNIPL YVAGSNGLFA YVFIDLIEFI SEDEKLQSVR
     PTTVGPISSN RSIIEVTTRK DEEDEKKTYE RIKTKNCYRP LNEVLSTATL KEKMTQRQLK
     RVTSILPLTL SLLQYGLNQK GKAISFEQMK RDAAVWCENL GVPATVVKDD YIQQFIKQKG
     IEFAPVAAII GGAVAQDVIN ILGKRLSPLN NFIVFDGITL DMPLFEF
//