ID B3NWC3_DROER Unreviewed; 1374 AA.
AC B3NWC3;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 24-JAN-2024, entry version 70.
DE RecName: Full=Protein xmas-2 {ECO:0008006|Google:ProtNLM};
GN Name=Dere\GG18199 {ECO:0000313|EMBL:EDV46462.1};
GN ORFNames=Dere_GG18199 {ECO:0000313|EMBL:EDV46462.1};
OS Drosophila erecta (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7220 {ECO:0000313|EMBL:EDV46462.1};
RN [1] {ECO:0000313|EMBL:EDV46462.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSC#14021-0224.01 {ECO:0000313|EMBL:EDV46462.1};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RA Clark A.G., Eisen M.B., Smith D.R., Bergman C.M., Oliver B., Markow T.A.,
RA Kaufman T.C., Kellis M., Gelbart W., Iyer V.N., Pollard D.A., Sackton T.B.,
RA Larracuente A.M., Singh N.D., Abad J.P., Abt D.N., Adryan B., Aguade M.,
RA Akashi H., Anderson W.W., Aquadro C.F., Ardell D.H., Arguello R.,
RA Artieri C.G., Barbash D.A., Barker D., Barsanti P., Batterham P.,
RA Batzoglou S., Begun D., Bhutkar A., Blanco E., Bosak S.A., Bradley R.K.,
RA Brand A.D., Brent M.R., Brooks A.N., Brown R.H., Butlin R.K., Caggese C.,
RA Calvi B.R., Bernardo de Carvalho A., Caspi A., Castrezana S.,
RA Celniker S.E., Chang J.L., Chapple C., Chatterji S., Chinwalla A.,
RA Civetta A., Clifton S.W., Comeron J.M., Costello J.C., Coyne J.A., Daub J.,
RA David R.G., Delcher A.L., Delehaunty K., Do C.B., Ebling H., Edwards K.,
RA Eickbush T., Evans J.D., Filipski A., Findeiss S., Freyhult E., Fulton L.,
RA Fulton R., Garcia A.C., Gardiner A., Garfield D.A., Garvin B.E., Gibson G.,
RA Gilbert D., Gnerre S., Godfrey J., Good R., Gotea V., Gravely B.,
RA Greenberg A.J., Griffiths-Jones S., Gross S., Guigo R., Gustafson E.A.,
RA Haerty W., Hahn M.W., Halligan D.L., Halpern A.L., Halter G.M., Han M.V.,
RA Heger A., Hillier L., Hinrichs A.S., Holmes I., Hoskins R.A., Hubisz M.J.,
RA Hultmark D., Huntley M.A., Jaffe D.B., Jagadeeshan S., Jeck W.R.,
RA Johnson J., Jones C.D., Jordan W.C., Karpen G.H., Kataoka E.,
RA Keightley P.D., Kheradpour P., Kirkness E.F., Koerich L.B., Kristiansen K.,
RA Kudrna D., Kulathinal R.J., Kumar S., Kwok R., Lander E., Langley C.H.,
RA Lapoint R., Lazzaro B.P., Lee S.J., Levesque L., Li R., Lin C.F., Lin M.F.,
RA Lindblad-Toh K., Llopart A., Long M., Low L., Lozovsky E., Lu J., Luo M.,
RA Machado C.A., Makalowski W., Marzo M., Matsuda M., Matzkin L.,
RA McAllister B., McBride C.S., McKernan B., McKernan K., Mendez-Lago M.,
RA Minx P., Mollenhauer M.U., Montooth K., Mount S.M., Mu X., Myers E.,
RA Negre B., Newfeld S., Nielsen R., Noor M.A., O'Grady P., Pachter L.,
RA Papaceit M., Parisi M.J., Parisi M., Parts L., Pedersen J.S., Pesole G.,
RA Phillippy A.M., Ponting C.P., Pop M., Porcelli D., Powell J.R.,
RA Prohaska S., Pruitt K., Puig M., Quesneville H., Ram K.R., Rand D.,
RA Rasmussen M.D., Reed L.K., Reenan R., Reily A., Remington K.A.,
RA Rieger T.T., Ritchie M.G., Robin C., Rogers Y.H., Rohde C., Rozas J.,
RA Rubenfield M.J., Ruiz A., Russo S., Salzberg S.L., Sanchez-Gracia A.,
RA Saranga D.J., Sato H., Schaeffer S.W., Schatz M.C., Schlenke T.,
RA Schwartz R., Segarra C., Singh R.S., Sirot L., Sirota M., Sisneros N.B.,
RA Smith C.D., Smith T.F., Spieth J., Stage D.E., Stark A., Stephan W.,
RA Strausberg R.L., Strempel S., Sturgill D., Sutton G., Sutton G.G., Tao W.,
RA Teichmann S., Tobari Y.N., Tomimura Y., Tsolas J.M., Valente V.L.,
RA Venter E., Venter J.C., Vicario S., Vieira F.G., Vilella A.J.,
RA Villasante A., Walenz B., Wang J., Wasserman M., Watts T., Wilson D.,
RA Wilson R.K., Wing R.A., Wolfner M.F., Wong A., Wong G.K., Wu C.I., Wu G.,
RA Yamamoto D., Yang H.P., Yang S.P., Yorke J.A., Yoshida K., Zdobnov E.,
RA Zhang P., Zhang Y., Zimin A.V., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Blye J., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., Grabherr M., Kleber M., Mauceli E., MacCallum I.;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
RN [2] {ECO:0000313|EMBL:EDV46462.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TSC#14021-0224.01 {ECO:0000313|EMBL:EDV46462.1};
RX PubMed=18057021; DOI=10.1093/bioinformatics/btm542;
RA Zimin A.V., Smith D.R., Sutton G., Yorke J.A.;
RT "Assembly reconciliation.";
RL Bioinformatics 24:42-45(2008).
RN [3] {ECO:0000313|EMBL:EDV46462.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TSC#14021-0224.01 {ECO:0000313|EMBL:EDV46462.1};
RG FlyBase;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SAC3 family.
CC {ECO:0000256|ARBA:ARBA00038443}.
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DR EMBL; CH954180; EDV46462.1; -; Genomic_DNA.
DR RefSeq; XP_001977535.1; XM_001977499.2.
DR EnsemblMetazoa; FBtr0138253; FBpp0136745; FBgn0110415.
DR GeneID; 6550138; -.
DR KEGG; der:6550138; -.
DR eggNOG; KOG1860; Eukaryota.
DR HOGENOM; CLU_003138_0_0_1; -.
DR OMA; RPHNSFN; -.
DR OrthoDB; 91913at2759; -.
DR PhylomeDB; B3NWC3; -.
DR Proteomes; UP000008711; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12457; RRM_XMAS2; 1.
DR Gene3D; 1.25.40.990; -; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR045107; SAC3/GANP/THP3.
DR InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR InterPro; IPR034366; XMAS_RRM.
DR PANTHER; PTHR12436; 80 KDA MCM3-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR12436:SF3; GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN; 1.
DR Pfam; PF03399; SAC3_GANP; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50250; PCI; 1.
DR PROSITE; PS50102; RRM; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 12..83
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 344..527
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 580..599
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1293..1317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1329..1374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 645..763
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 581..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1330..1345
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1358..1374
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1374 AA; 158064 MW; 2493C47143B4622D CRC64;
MAEPRPGAYN YKTLLCTNIP ELFLDKYVAR SHFGRFGTLV NFVLRPRRMT CTVSYASEEQ
AERALLEGDS FQGHQFDISY AENETAPAQK TEEWVDPDVQ AELSALQSGW RNEYASGKPL
KPSLSGAPML PSLPAAAATA AVSVKNPPAT RDRTPAQLRD LENVMRRPAH TSEEKFRVLD
ARDKLLRMNR TQQKPVAGAT QGHCPDMCPE KERVLREFQR QVAVYELQPG SDELICHERA
LKQYSRSSAD QETPLPHELR NETALHMTMS YLMHEIMDIS ERQEPQSYLG DWFHFVWDRT
RSIRKEITQQ ELCSLGAVKL VEQCARFHIH CAARLVAADP SVFDSKINAE NLTKCLQTLK
YMYHDLRLKG VQCPREAEFR GYIVLLNLAD ANFLWDIGQL PAELQNCPEV RQAIQFYLAL
HDTNFVRFFQ LLMDEDTSYL SACILVTYFT RLRVLGLHRL IQAYRAPRKD EVSSLPLSYI
ADLLSFASEQ EAVDFVQHYG LELNETGRVV LSRMHTVETE YKLPRQYELV EMKRVQSVGE
VVSGEPLPPR ALYLNHRPHN SFNEHGMLKS IAWTAKDQLP GMQQEDVQPQ IPSHPPAASK
QSDNFFKVPM QPDGTATGFG APATAAVAPA STIEAFSFVL PKSRAQELQE QAVAEQQRRA
QEEAKHQALQ IAIAAAKKRE AELMAIHEAK VAEAERIRQQ KLRERQEQQR RQQEELEAQR
QQEQEKLQLE KERQLKLEEL RLLQQQEREA RKKTKTLECY QDTFQDILAE VCSREFKLHD
QACCSYESVL DSLTRGLVEQ QMQQSLYELG IMRVYIKRWR NYRRVQQQKD TLFNQLPLSF
RADDTDRLVN ERTVEDSLRL IRRYRLGEPC DYGKLLAGLE EQSWLKLDLW RVLDKCLPLA
QPGARRFYKL LLSLSGGQEG IQLNYDLDKG LLQQPQSPDA RLAEGGYIRG FSQGIGLSVL
KIRDNHHDWK ATDLAQANGI ICLIGLEDFR SLKQRLRPLL QASRCLDVAV IVQHPANTAF
VDLDIPLQDL CLRSFNVFRV RHSGNTSQRL MHALEAAVKY LAKATERKPF EHLQQVETRE
FVLGNLGSEL FRRLKHAAEQ DAAIRRGIRL NPQFCADLFN EAVQRLQLVA GEDLSDCPQF
PDELRVFVQP LPIESSVPTK RLEHFEPGWH LPERRQRIVQ LLERCKLPKM SELPGTSSLA
EAQCQWVLDY AQLSQQEDCV EQIALQAIQI LQSNADGYLN FVEYLAGERM LYILGQERNL
PLGVVYKTKT LKSRFLGAWF YEFREPQTYE AAAAEEDAQE QEEQEQQPSQ AEEQQLDFNE
IMSKAEAVLN RCRQRQEDRH TLRDLNRSHK TRKGKVAPKQ KHDAENKPKR KRPN
//
