ID B3QNJ3_CHLP8 Unreviewed; 747 AA.
AC B3QNJ3;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:ACF11496.1};
GN OrderedLocusNames=Cpar_1088 {ECO:0000313|EMBL:ACF11496.1};
OS Chlorobaculum parvum (strain DSM 263 / NCIMB 8327) (Chlorobium vibrioforme
OS subsp. thiosulfatophilum).
OC Bacteria; Chlorobiota; Chlorobiia; Chlorobiales; Chlorobiaceae;
OC Chlorobaculum.
OX NCBI_TaxID=517417 {ECO:0000313|EMBL:ACF11496.1, ECO:0000313|Proteomes:UP000008811};
RN [1] {ECO:0000313|EMBL:ACF11496.1, ECO:0000313|Proteomes:UP000008811}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 263 / NCIMB 8327 {ECO:0000313|Proteomes:UP000008811};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Zhao F., Li T., Liu Z., Overmann J.,
RA Bryant D.A., Richardson P.;
RT "Complete sequence of Chlorobaculum parvum NCIB 8327.";
RL Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001099; ACF11496.1; -; Genomic_DNA.
DR AlphaFoldDB; B3QNJ3; -.
DR STRING; 517417.Cpar_1088; -.
DR KEGG; cpc:Cpar_1088; -.
DR eggNOG; COG0475; Bacteria.
DR HOGENOM; CLU_017738_0_0_10; -.
DR OrthoDB; 9793589at2; -.
DR Proteomes; UP000008811; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR43562:SF4; NA(+)_H(+) ANTIPORTER NHAS5; 1.
DR PANTHER; PTHR43562; NAPA-TYPE SODIUM/HYDROGEN ANTIPORTER; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF00582; Usp; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 25..390
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT DOMAIN 418..541
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
FT REGION 723..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 726..747
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 747 AA; 82860 MW; EA266B18082E63CB CRC64;
MEHYYVELLQ EFQLPLTNPV LIFSLVLFII LLSPIVLKRF NIPGTVGLIL SGVLIGPYAL
NLLEKSSAVD LFSTIGLLYI MFIAGAELQV NELKRNRNQS LLFGLLTLIV PIVAVYPVCR
YLLNYNVSAS LLTASMLATH TLVAYPIVNR MGIAKNQAVP ITVAGTILTD TAVLLLLAVI
IGYSQGNLTQ EFWLHLAISL TIFTMIVFIV LPFIARWFFT KLENEKHAHY IFVLSAVFFS
AFLSRVAGLE PIVGAFAAGL ALNRLIPNSS ALMNRIEFIG NSLFIPFFLI SVGMLVDLRV
ILSGPMTLII AALLTVVALA GKWLPAWVTQ KLFKLSAAQR QLIFGLSSSR AAATIAIVLV
GYQARILDLN ILNATIILIL VTCIVGSMVT EKAAKEIVVE ESQASPVDES DEASFSEQIL
LPIAEGLPSE RVLEFAVLIR EKRSAKPLIL LSVVPNDHEA ELNMKKSKKA LEPMINYAAS
FDTKLDIVAT IDYNVSSGIS RMARELQADL VVYGWPLHRG FIARLINDSA ESIVNCTSKT
TIICQITQPL ALHRRLVVII PPLAEMEKGF EQWVAKMTLL SLELSIPMEL HCNSKTHAAV
LDSFDSMQSA PKLLFEPMKN ARDWENLSRQ RKRFKDDDII VLVSARKDSL SYKPYFDQSP
EQLEKHFGGI SKIMIYPASY GAANIAEGYV DVVVPEPIRI GASAIRKVGN ELGLFLKKNQ
QQIRKKIRDK RQNQQKTQDT TEKGDKP
//
