ID   B3RH78_YEAS1            Unreviewed;      1026 AA.
AC   B3RH78;
DT   02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   02-SEP-2008, sequence version 1.
DT   22-FEB-2023, entry version 40.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN   ORFNames=SCRG_04146 {ECO:0000313|EMBL:EDV08522.1};
OS   Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=285006 {ECO:0000313|EMBL:EDV08522.1, ECO:0000313|Proteomes:UP000008335};
RN   [1] {ECO:0000313|Proteomes:UP000008335}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM11-1a {ECO:0000313|Proteomes:UP000008335};
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA   Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA   Kruglyak L.;
RT   "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS981519; EDV08522.1; -; Genomic_DNA.
DR   AlphaFoldDB; B3RH78; -.
DR   HOGENOM; CLU_006977_1_0_1; -.
DR   Proteomes; UP000008335; Unassembled WGS sequence.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
FT   DOMAIN          102..221
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          623..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          813..993
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1006..1026
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        636..651
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        813..886
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        901..981
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1026 AA;  114050 MW;  2EE446645377117F CRC64;
     MKRIFSGVKS PKLSAPPKVF KNDESPSTPS SPKFDQGLRS LSASASRLFS NSISTPGSPT
     LDLPQEHSIN GDISPELVPI VTLLSAQAHR RYHYGIFLIL HDLKTDGTPA VRQWEECYGV
     LLGTQLALWD AKELSDSKNN KNTSTMKKAA SRPSFINFTD ASVRSLDAND QVISASENEK
     TKKDLDNVLV VSTTLKNRYF LKFKNSKSFK TWNAAIRLSL FEFTALQEAY TGSFLSSRGV
     KLGDIKVVMA DTKFTYEDWV SVRFGTGMPW KRCYAVISPQ SGKKKKNSKG SICFYENNKK
     TKKSNIMTTV VDARALYAVY PSSPILIDTS TIIKLEGFVS FDKSEEPQET NLFIMPEKHQ
     GVPGYDTIIR FLIPAMNAFY LYGRPKGLIA NRTDPDSLLF ALPTLPHIYY LQVDDVLSLT
     KDKNYIHWSA ADWRNNIVQV LQKKLSKGYK GCGNKSVSVS SGMMKSPAIS SAELFEGYDS
     LPERQMESPQ KSKMKSPTLA STDDINSASA SVNSHAISVK QTELFVTDNS SKINDSVSAQ
     SSVTTNFKDT FTTPMTSGML NQENSERSFG SGLKLKITDS NLENMEDVEA KSANEFSTTP
     EDKHIHLANA AELSALYDKY STSPFGKSEA NSSPKPQKLE VKDRSKNENR SPYERYVGTS
     AESKTFEIGN VRESKSTINT SLSSPLRVED SRRSKNEDLG SLKEFEELSQ KISNMGMANI
     SSEALSDTAE NSSFVTDLNL NINNSSSVNL NEEQRVPDFG EENVFDPDYM EQNQMLETES
     RYTTDEFDFS DNQDAASSNY SNGQTNRTVT ETLSASDRND KIPHSSLFTN LNQLTSNGGN
     YQDREDFSGD QINKPQQSQP LHVKGPQTSS FGYRNSSANS SQPQAPYPVG RPLGKIRTGP
     LTVQPIQQGG NSSMYSFQSS QHRFHSSQQR QNQSLSFRNN TYGSGNNQNT LHPSPQLQQQ
     PQNMRYLNNK LPINDRSPIP QTQHHVPDGR PSLHINTTNR TNPLTAQSGF SQFMPPNSTS
     TNPYSS
//