ID   B3RJK1_TRIAD            Unreviewed;      1658 AA.
AC   B3RJK1;
DT   02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   02-SEP-2008, sequence version 1.
DT   24-JAN-2024, entry version 50.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EDV29831.1};
GN   ORFNames=TRIADDRAFT_52656 {ECO:0000313|EMBL:EDV29831.1};
OS   Trichoplax adhaerens (Trichoplax reptans).
OC   Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC   Trichoplax.
OX   NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV29831.1, ECO:0000313|Proteomes:UP000009022};
RN   [1] {ECO:0000313|EMBL:EDV29831.1, ECO:0000313|Proteomes:UP000009022}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV29831.1,
RC   ECO:0000313|Proteomes:UP000009022};
RX   PubMed=18719581; DOI=10.1038/nature07191;
RA   Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA   Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA   Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA   Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA   Rokhsar D.S.;
RT   "The Trichoplax genome and the nature of placozoans.";
RL   Nature 454:955-960(2008).
CC   -!- SIMILARITY: Belongs to the APC1 family.
CC       {ECO:0000256|ARBA:ARBA00010547}.
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DR   EMBL; DS985241; EDV29831.1; -; Genomic_DNA.
DR   RefSeq; XP_002109033.1; XM_002108997.1.
DR   STRING; 10228.B3RJK1; -.
DR   EnsemblMetazoa; TriadT52656; TriadP52656; TriadG52656.
DR   GeneID; 6750247; -.
DR   KEGG; tad:TRIADDRAFT_52656; -.
DR   CTD; 6750247; -.
DR   eggNOG; KOG1858; Eukaryota.
DR   HOGENOM; CLU_001202_1_0_1; -.
DR   InParanoid; B3RJK1; -.
DR   OrthoDB; 180933at2759; -.
DR   PhylomeDB; B3RJK1; -.
DR   Proteomes; UP000009022; Unassembled WGS sequence.
DR   GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR   GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR   GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IBA:GO_Central.
DR   GO; GO:0007091; P:metaphase/anaphase transition of mitotic cell cycle; IBA:GO_Central.
DR   GO; GO:0070979; P:protein K11-linked ubiquitination; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR024990; Apc1.
DR   InterPro; IPR048971; Apc1_3rd.
DR   InterPro; IPR046794; Apc1_MidN.
DR   InterPro; IPR011989; ARM-like.
DR   PANTHER; PTHR12827:SF3; ANAPHASE-PROMOTING COMPLEX SUBUNIT 1; 1.
DR   PANTHER; PTHR12827; MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER; 1.
DR   Pfam; PF21282; APC1_3rd; 1.
DR   Pfam; PF20518; Apc1_MidN; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          583..684
FT                   /note="Anaphase-promoting complex subunit 1 middle"
FT                   /evidence="ECO:0000259|Pfam:PF20518"
FT   DOMAIN          1399..1477
FT                   /note="Anaphase-promoting complex subunit 1 beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF21282"
SQ   SEQUENCE   1658 AA;  187298 MW;  09F053DB4054A497 CRC64;
     MEDFIPNGKI YYRDRHPLGK NDENGHQEQK DFWKVTCYAD DQDGGNVATE KEIYVCDKTV
     VLSFSGIGDT NKIVKTFTVE TPIIDVSHHG AKNQKLCIIE QNFISFYAED GSFFTSSTPF
     PVQHVWNIST GLLIQRRFTE SEYEKHGKRI PELYTISNPI DEPHPVFINL ESGESKYFYG
     PEYQVVTTIR EPEFILIFDK NRNKHSLWQP RKLKTENTSD SFNTDPLASV NFTDQRLHNL
     TTKSQNLHHS AALSPFRSYT PPPVNSSIIS HHRNTPVSTL IPHMPAQQVH PLQGRDDINR
     LQQHPTIGHQ TPTASSIQLS LNRQGRDFSF VKTNIYSTEP LQPVLSEICL SKIWEEDICL
     ASVAKKAFFA TDFYGRKYFY CLVGDQLRVY QYHDMNFEYK LTIESKDVAC MTETGIIAVL
     DNASNGYFYN GLLQICQLNF DLWKIPGSIQ FLYQWAFDTL IVTNNYGKMF RIPLLKLPSN
     VIVKSSLAAL HQLLPEEIGF TILAQYLKAS VNKSYDNIEC SLEVFVRFLL WLISEKGSLE
     EVSGTGTRIG TDIWSAVLQT PIHARYTKED LLDVIVTKCI KPDKNWIGYQ HLPSILFSLH
     LIYEEFKLDS TAATSLYPLA QFLYFCASIL DAKFYLDYYR RDFPKLFTYN LQEVVPTERL
     SQTMPSYITS YPINVRNWMI QCFRRLKICT KFTGNEEAIA EPIFRYEYYI FDINNRDQIL
     NSSDVYISWK LHSLTFGVQI ILHQILNDCR RNPSGSWPKL AYELINRQDL IGQTKLRSNR
     QRFSDDQTKA TNEILEEDVD ESTSVSNKVT NLIFGKDLRL REVGRLLRSS KPVPVSVARK
     PESSDHEYIE QQEEWLYTIS QRTMALPVGR GMLTLFKSSP IVAEVVSIPS LNLTGRIPPK
     NAIIKLEMSN YPGLTDWPLF HNGVAAGISI MPGLSQIDST WIVYNKPQNE QSTNEHAGFL
     MALGLSGHLS NLKATSIHDY LSMGHSMISI GLLLGIAAAK RGTMDLAVTK MLSVHIRALL
     PPTSAELNIS QDVQIASLIG IGLLYEGSLH RSMVKMLLIE IGRGPGPEMD NCTDRESYSV
     AAGIALGMIT LGRGDCSPGL SDLTISDYLY NYIVGGNKDV TKRAIDEKSS PSSYLIKEGV
     NINVNVTAPG AILSLGLMFL KTNNRSIADW FIAPKTQTLL EASRPDFLLL KTWSRYLIMW
     DSILPTTAWV ENQIPPIAQE HGFSNVKVDK TLDYELLSQV KLYITAGACM AIGFRFAGSA
     NAEAFSTLTH YLNFVIKLQQ NPRISEEAGK CTIEMCLGTI CLALAMVMSG TGNLTVLKTL
     RKLHSQLGST EINYGRHMAI HMSIGLLFLG GGRYTLNTTN ESVAYLVASL YPYFPANSCD
     NKYHLQALRH LYALASQPRI MVTRNIDDGD PVYVPISVTL KATENYQRCK LNLTTPCLLP
     ELHLIEQVKT NSCHQYSFKC LLKALLDNHG TVFVKRRAGF LNYKSDPKGL QNALARDFSI
     EKESLFCQPS KINKIKSLTS NKNLLAFAEF LCNNTKNDTE TLISNELLEY IKSYVSCYML
     DDITGTFKEP DTFLEYVKDG AKLITANLGT LEHLASFLQL YDVPPAYQIF GINEDGGYPS
     DLLSLFMKFG GNPPAETVLR VLPVIKMISS NKDNMDYE
//