ID B3RQ10_TRIAD Unreviewed; 2016 AA.
AC B3RQ10;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 101.
DE RecName: Full=Mucin-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIADDRAFT_53736 {ECO:0000313|EMBL:EDV27739.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV27739.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV27739.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV27739.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS985242; EDV27739.1; -; Genomic_DNA.
DR RefSeq; XP_002109573.1; XM_002109537.1.
DR EnsemblMetazoa; TriadT53736; TriadP53736; TriadG53736.
DR GeneID; 6750788; -.
DR KEGG; tad:TRIADDRAFT_53736; -.
DR CTD; 6750788; -.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_237054_0_0_1; -.
DR InParanoid; B3RQ10; -.
DR OMA; DSTAYTH; -.
DR OrthoDB; 1114672at2759; -.
DR PhylomeDB; B3RQ10; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0007160; P:cell-matrix adhesion; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 16.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 23.
DR InterPro; IPR005533; AMOP_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR024731; EGF_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003886; NIDO_dom.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR InterPro; IPR001846; VWF_type-D.
DR PANTHER; PTHR24039; FIBRILLIN-RELATED; 1.
DR PANTHER; PTHR24039:SF28; FIBULIN-1; 1.
DR Pfam; PF12662; cEGF; 2.
DR Pfam; PF12947; EGF_3; 8.
DR Pfam; PF07645; EGF_CA; 10.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF06119; NIDO; 1.
DR SMART; SM00181; EGF; 23.
DR SMART; SM00179; EGF_CA; 22.
DR SMART; SM00539; NIDO; 1.
DR SMART; SM00216; VWD; 1.
DR SUPFAM; SSF49313; Cadherin-like; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 8.
DR SUPFAM; SSF82671; SEA domain; 1.
DR PROSITE; PS50856; AMOP; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 20.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 18.
DR PROSITE; PS50026; EGF_3; 20.
DR PROSITE; PS01187; EGF_CA; 9.
DR PROSITE; PS50024; SEA; 1.
DR PROSITE; PS51233; VWFD; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1914..1938
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..52
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 53..93
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 94..134
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 135..175
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 176..216
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 217..257
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 292..332
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 333..373
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 374..414
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 415..455
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 456..495
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 755..893
FT /note="AMOP"
FT /evidence="ECO:0000259|PROSITE:PS50856"
FT DOMAIN 905..1103
FT /note="VWFD"
FT /evidence="ECO:0000259|PROSITE:PS51233"
FT DOMAIN 1353..1393
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1394..1433
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1475..1514
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1515..1556
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1557..1598
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1599..1638
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1639..1676
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1679..1789
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 1830..1870
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1871..1905
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 1956..1992
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1956..1970
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1971..1992
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1398..1408
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1479..1489
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1895..1904
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 2016 AA; 226412 MW; 77A08B30C86F4900 CRC64;
MANVPLTCKI ADINECTGNG SLCDLNANCV NFNGSYNCSC KTGYQGNGVD CFDIDECSFK
QDQCHSQAIC TNTKGSYSCL CKMGYTGNGF VCEDINECRE GSHACDRNAV CINTNGSYFC
SCKDGYTGNG TACYDIDECS LGLHDCNIYS ICIDTVGSYE CSCKHGFVGN GSYCQDIDEC
LENKHNCDAN AACHNTIGSY TCSCNTGFTG NGTFCNDINE CTETKNDCSS NAACNNTIGS
YFCACKVGFI GDGVTCQGDE KSFLTRCYIQ PLVNQANFTN ITRIVVYICC LDLNECAAME
LYCHNNSVCY NTFGSYHCTC KTGFTGNGKV CEDLNECSQN QHNCGINSIC NNTIGSYSCT
CKPGFSGDGK ICLDVNECLN NLNNCHSDGI CSNTIGSYIC TCKSGFTGNG FQCQDINECT
ASNFVCHSKA FCSNTIGSYK CTCKTGFTGS GKYCTDINEC RISNKCSKLA NCYNTYGSYD
CVCKYGLQGD GHWCGQTGTR LYPYGTQFGH NWFGRTDQGY AYLYIPEGIY FVRSLYRRLY
ISIDGYVSLK WPYVGYWPKP FPEPLRRSII APYYADCDVR YQSTSKVYYK QYYSHQNDPL
AQEIIKNATN DVNRFQHRMR FDNQKAKYGR FRQVVANFEA AHVIIITWHK MTPYPAWYYW
YYPYYRQYNT FQLVLVSNGE NLFALYNYEE NGINWWKRFW WIRPRVGYSY GVKPYFYEIP
ISRRRHQRVS MIDRYRGNTG ELGKWAFRLD DPNSRHVNHA YQCYRWYYGQ SYSYWYQIFL
QPCPCRSWQA IWDPRFRFDW RTQCATSRIS VPGWGWWWYW WYWIYTGRWT SPSPVRQRCC
YSTQKYSWGA LLRNYPDGSS FRYNSWYLRR LDEKAYDSCC RQTDLCHLYI TRRPINSCAG
YWPPWWSWFW GDPHVQTLDG KRYTFNGLGE YTLVDASNKY FVLQGRTMRS VVANSTERAK
ATVFSAFAAT QNDSDIVQLT LNDTSDTVSL LINRTISIND DNLTNVTLSY NNVDISKSNG
SYLVVFSSGI SLEISHLTKM LTIAFAAPQS FRETTKGLLG TWNGNVSDDF LRPDGTYLDV
NATEEDIYYS FGEEWRITDE ESLFTYPTGI STDNFTDPNY VPNFSKDPEV LFKNDTELKE
KALKICGSDR TCLYDVAETA NLQLAARSKD IDQQYERVQK DIENFPPNIT GQKIYNVTYG
QQFTTKLNIT DQNVNDNLTI QISNLPSDAS FNRDTSRFTW NVTTYSNISF EFIATDSKNL
TTVFKPTIVM CYCANGGTCQ YEFEITTVNG EEYAGCRCTT AWTGRFCNED FDECAGNPCY
EGVNCTGKIA PESGYSCGSC PNGLEGDGEK CYDVDECLMG VHSCNQTCIN SIGSYTCQCN
IGFKIATNQR DCEDIDECVQ SEPCHQICNN EYGHYRCACN PGFELDDNNS TCLPLISCDP
GLSNCTQICA VINDSAICSC NKGYHLAEDN TTCDDHNECA NPSICAHLCT NTIGSYLCSC
KNGYQLSSDG RNCQDIDECE TENSTLCHEN SLCTNLPGSY FCECDEGFKL SGKLCEDIDE
CSTSNLNECD RNANCINMEG TYNCICKEGF NGNGIECMDI NECGNANNCS KDAVCSNLPG
SYNCSCKAGF TGNGLVCQDV DECQNAFSCN TESICHNTIG GYYCSCKKGF YLYRNVTTGI
SQCQGLIRLN GTYTVALDNP ESQAYVLLKT EVVTKLTVVF SNDSRTQDRV QQISILSIRP
GSILVNFTLT LLQNATSVTT DIIREIAENG ITRIGDYPVT SFHIKDYNDC VDPQANTCSS
LQSCTNTMGT FSCQCISGYS WNSESNQCED INECLLNATC ASNAICVNIF GGFKCQCEKG
YTGNGLRNCS SLCPLHFCQN DGQCLYLNDS FICNCTSEFY GPSCENAVST VNTVAVIGIA
LGSVVAALVI ILLAIYLWKK FYSTYKVSDV VNLSSSDADD RNDADNQDNS DHGSSRSSSR
STAQQARPNR RSCFWLSKTS DYDSYTSFDA NTTENQ
//
