ID B3RR18_TRIAD Unreviewed; 1564 AA.
AC B3RR18;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
GN ORFNames=TRIADDRAFT_54078 {ECO:0000313|EMBL:EDV26803.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV26803.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV26803.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV26803.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
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DR EMBL; DS985243; EDV26803.1; -; Genomic_DNA.
DR RefSeq; XP_002110799.1; XM_002110763.1.
DR EnsemblMetazoa; TriadT54078; TriadP54078; TriadG54078.
DR GeneID; 6752012; -.
DR KEGG; tad:TRIADDRAFT_54078; -.
DR CTD; 6752012; -.
DR eggNOG; KOG1840; Eukaryota.
DR HOGENOM; CLU_245785_0_0_1; -.
DR InParanoid; B3RR18; -.
DR OrthoDB; 614488at2759; -.
DR PhylomeDB; B3RR18; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0097546; C:ciliary base; IBA:GO_Central.
DR GO; GO:0097543; C:ciliary inversin compartment; IBA:GO_Central.
DR GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR032171; COR.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF16095; COR; 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 4.
DR SMART; SM00028; TPR; 11.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT REPEAT 127..160
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 295..328
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 379..412
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 421..454
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 1194..1384
FT /note="C-terminal of Roc (COR)"
FT /evidence="ECO:0000259|Pfam:PF16095"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 861..891
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 867..883
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1564 AA; 180469 MW; 29F0E0D0713F9EA9 CRC64;
MENQEGGNLL RSHDSSNEEN QPKVKAIRSG GMKVNVFLTR EIQSKRQMGR YYFQQGEYQS
ALINYKAILD KMVDPVDITI EQDCYQCDIL LDISDTLREQ YHYDDAQEYC IQAEKIAKKV
KDKLRLAKCY DNHGKLNTIR NHYQQALEDF NQALEFKLSL LDDRNLHVSD TYHSIATVLY
LVDENSQALV MYQKSLNIRL NLLGDENLYV AYSYHGIANI YRKQHQYDDA LTMYQKSLLI
QLAILGYNHV SLVGIYNAIA TLHCSPSKCN NAVKIYQKSL DMKLEIFNKY HLDIADTYHG
IGNVNYLQSR YDDALKLYQM ALDIRLKLVG NCNLYIAQSY YAMGNIYYYQ DKIEEAQEMH
EKSFNIRLAL LSDNHLLVAQ SYYMLGQIYL SLANYSDALS YHQKCLNIRL KVLDDENLLV
AHSYHAIASI YHKQSDYDTA LTMYKKSVQI KLQLFGNNYD VAYTYDSISS LYLDLGQHYD
ALSWCQKSLT IGLTLFGENN PFIANLYDKI ATICERQEKF SEAATAHQIS SNDNNDIPLE
KFNRILNEDQ ADGNIDSSDL EYSWAIPSTP KTPIKEISID EFIDLYQKNG NSSKRDKVMM
DALSDSIEEK EVQETNDKNN NSTRSRSDSR VLLKVTEESI EKMIEELSDP EDAQEKVLSI
TGGMLYKSDY DDENVRQCQF GARTILDFTE DLNEGTIQNW RDIGGSIDCF QDSLRTTLKT
IIESSEGEDN DLSEMQEQSV NVDTENHANG KKEGVTEDNF LSNLFKIVID SKRRNDFVRL
MFIGLSNAGK SSVIRILTQN GIIENLQSTK IINTNNEVVN LIHDDSSTNP WICDFIKVLN
QKLATSIDSV KRELIKNLPA AHDGNGVDAK NNNNSSITND HGENKHLSGT EKKAEIVKDP
YLVIDREKKE VIQMVVDHQQ EDQIETRHVA HNSTTLLVNS SSEETTLSTH ISNQYQALGK
LAVNKYFRSI LEALEATVQV NHDRYGSLWE FCGQTMYRCL HYPFIPGRGI YILVLNVTSD
LSNTQDDQSA NIADLEGLHE WLTLIIGSSD NREQIKMTVD GIDEEYSWPV IVLVASYIDS
AREQYQLEQR FKQVEQQLIS SLPPLYRCHI YSSGILFNCN PNDNSQATVS QRLQSSRNLL
HIVGKITDIL PFMNDLIPIR WYMMTILLQP KPFTNKENNT MFPNGMKQNI SNPVSNIMTM
QQMQQFAIDH GLYKDDQDLH DMLMYLHDFG KILYCYHKVD DRIIVTNINW LLNILYTISA
LEEHQFHSAA IRHDYQVART TGKMSELCLN YAIKRFHLGS NEKEIILRLM AYYHIACQIK
SNRIDHQNEE RQFFVPYILQ TNTNELELTG YHRSNWLYIG FDRNDMNCIP DAIFYCLLVS
CLNQWNNPQI KVFNQCAQYS LQDEDYEIIV RKERSYIGLQ YCYQIIEDKD LADLVLNNIK
LSISDKRPHD MIREQLSEIV AKRMSKFKKA SCQYYVKCPK CLLPTCTARC YQNNPCVIRC
QCNQVFKSKS VEEWMMGKSI DLCMEKDLNS KEGPTESLSS IPVKTAEKLR RSVSIRARRY
CDVQ
//
