ID B3RW62_TRIAD Unreviewed; 1204 AA.
AC B3RW62;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TRIADDRAFT_55897 {ECO:0000313|EMBL:EDV25610.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV25610.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV25610.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV25610.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
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DR EMBL; DS985244; EDV25610.1; -; Genomic_DNA.
DR RefSeq; XP_002111643.1; XM_002111607.1.
DR AlphaFoldDB; B3RW62; -.
DR STRING; 10228.B3RW62; -.
DR EnsemblMetazoa; TriadT55897; TriadP55897; TriadG55897.
DR GeneID; 6753371; -.
DR KEGG; tad:TRIADDRAFT_55897; -.
DR CTD; 6753371; -.
DR eggNOG; KOG4225; Eukaryota.
DR HOGENOM; CLU_270451_0_0_1; -.
DR InParanoid; B3RW62; -.
DR OMA; YQNGNAY; -.
DR OrthoDB; 5407056at2759; -.
DR PhylomeDB; B3RW62; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR GO; GO:0016477; P:cell migration; IBA:GO_Central.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd11780; SH3_Sorbs_3; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF30; ENDOPHILIN-A; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50002; SH3; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 24..78
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 788..847
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 859..918
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1136..1197
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 936..1127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..456
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 615..665
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..682
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..760
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 936..967
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 985..1018
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1020..1046
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1086
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1127
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1204 AA; 136291 MW; 3D0817593D64DDA8 CRC64;
MTKFVNQRKT TSILRRKAKG PDKNQVNENS KAEAEDMRVG DIVKSINGTN CDNMTHSEAL
STIRRAGMRL QIVLERQDRN ANDGYGNMQS YRSGAQHYDS HSGQDYQPSG VPGNHGGGTR
ITIGNNRRSR ASQDDYDHYQ QPNDGNNYQG NYQKPSNATY GQNTGGNYNN GYGPSDNNQN
DGKNPQWPGK NSWVPNDNNT HKTANTNIND SRRQSNYRNR SNSRIRAKKS VASKRQFIQE
FGHVNSPTRK LVKNTNSRNL YIPSYDDPLQ PLPGHEPQEE PDAAPLSPIL TKFEKPPPPR
YRRMPTREGL RNVYSSPDYF SRGGFDNVQP INLKVPALNL LHRQRDFVNR EDDEEGVIVH
SAYRSKNRKK INKINKAMDG AVKDNIDRSS TKPNSLALQS PTTSSSDQSP VINSRKNKTT
KINSTSPTRE TTKLNVRNKI GSYDKTKSNP IISSRKENEI GKNKEKLVKP LSQSSGNKSK
VVVRTSLPKN AADNNGDRSK VFPKKKNSTA IKSPATNVAK KDRKTTRLKI RKNNSAPESP
TSPVEQINAT SLEALESVDN NSSNEEPPPV RIPAKPDSYR PTHQDYEDDW SNNDQGGGFW
PQKSNDRKED DSSGGRSYNT LPNQRNQNSF QPIQPVGPQK SLSRTGSVKS LGNDYNQNQY
NEQYDPKYQP RYGDHEDYRP GGGWQENTRI GNSHSKSTPS LAQPEDDNEP YGRNKYYDDR
NDNHDSHYRD QQSRPFHRDD SDSRKPDSRK YDDDTDYPAK MPEKANFNVI DEKGLMFDPP
SNYNIHDKTI PKCKAIYSFK PASKRELALK KGDLIILTKN VDKNWYEGEL HRKRGIFPAN
YVEVVTSIKE ALAAQCEYSQ DGLGQARRDC NGITSKELSF SKGQIITLLK HVDANWFEGR
LNSRSGLVPK KFLNVLKDVK GAGTMKQARN NKIQDFSEAS SRPNKHVIGS DSNQYNPKAY
GQSREFDDNN QQVDDRYGYY DSKPQYQSGD YNYQSQENDP YSQDGKSGRN SYYNKQDFDT
RSAGGRDFDT RSAGGRDFDT RSAGGRDTST RYEAGGDPYE SKPQQRQGGG IDNRNSNNYG
DYNRRSQRYQ SETDYSDNHS QSGIRAKNNE FDHNNNTNYY NDGAADNSNY SQANTETSER
YRAFYPYAPE KEDELELMVG DIIIVKEKCD DGWFVGSSTR TGLYGTFPGN FVEPVSIDSL
IINY
//
