ID B3S5X6_TRIAD Unreviewed; 589 AA.
AC B3S5X6;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};
DE Flags: Fragment;
GN ORFNames=TRIADDRAFT_11804 {ECO:0000313|EMBL:EDV21989.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV21989.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV21989.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV21989.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362056};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362056}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the organo anion transporter (TC 2.A.60) family.
CC {ECO:0000256|ARBA:ARBA00009657, ECO:0000256|RuleBase:RU362056}.
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DR EMBL; DS985251; EDV21989.1; -; Genomic_DNA.
DR RefSeq; XP_002115626.1; XM_002115590.1.
DR AlphaFoldDB; B3S5X6; -.
DR EnsemblMetazoa; TriadT11804; TriadP11804; TriadG11804.
DR GeneID; 6756736; -.
DR KEGG; tad:TRIADDRAFT_11804; -.
DR CTD; 6756736; -.
DR eggNOG; KOG3626; Eukaryota.
DR HOGENOM; CLU_008954_1_2_1; -.
DR InParanoid; B3S5X6; -.
DR OMA; CHRSINT; -.
DR OrthoDB; 2874223at2759; -.
DR PhylomeDB; B3S5X6; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd17336; MFS_SLCO_OATP; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004156; OATP.
DR NCBIfam; TIGR00805; oat; 1.
DR PANTHER; PTHR11388; ORGANIC ANION TRANSPORTER; 1.
DR PANTHER; PTHR11388:SF100; SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1; 1.
DR Pfam; PF07648; Kazal_2; 1.
DR Pfam; PF03137; OATP; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|RuleBase:RU362056};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362056};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362056};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362056}; Transport {ECO:0000256|RuleBase:RU362056}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 52..74
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 81..102
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 180..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 228..251
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 332..358
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 370..389
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 477..503
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 524..547
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT TRANSMEM 567..588
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362056"
FT DOMAIN 12..589
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT DOMAIN 405..462
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EDV21989.1"
FT NON_TER 589
FT /evidence="ECO:0000313|EMBL:EDV21989.1"
SQ SEQUENCE 589 AA; 65462 MW; 8981961659049BBA CRC64;
FRPQWLQVFN NSFWLLIILC YFSTIGTAFL GFKAVIAPIL EKRYNMTSTE VGAIMSSADI
SAAINGILLT FYASQKHKGR WIGYSLLLYI VGTMLFVAPH FLVDDYYYLE DDSGKTLCHR
SINTTSIDEK CSKSYEPSTF WICPFLFVLG QILCGAGNAT RYNLSVAYLD ENVSPIISPL
YVGIIHMMSI IGPTLGYVIG GALTNVYVDW PKDPPNGLTS NSVAWVGAWW INYLGIVVLI
ALTVLFVFAF PRHLPSYYNT RQERIKEATV ATQHMDYQYG NRMIDLPKAI KQLLSNKIFM
FASFGITVDK VAINGLTMFL PQYIQAQTGY SLLVASMLGG GLISFIASVG QVAGGYVIKR
WKLKGSQISR FCFFTSICNF LLGGVYLISC PNIPIAGVNI PYANITYKAA CNSHCLCDSV
PFEPVCGGDG ISYLSPCHAG CSSLKESDFN NNLVYKNCTC VPSATPGFCQ VPICQPLYAL
MIGITFSVIA AYISYSPTLT VILRNVPESQ VSFALGVLGF MKRMIGGLLG PIFLGIVMDK
ACSLWNIECD HNQFCWQYDN RDMSKNMFIT MIVFKGMQVI IYAVLWYFH
//
