ID B3S768_TRIAD Unreviewed; 480 AA.
AC B3S768;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=TRIADDRAFT_60061 {ECO:0000313|EMBL:EDV21517.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV21517.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV21517.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV21517.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS985253; EDV21517.1; -; Genomic_DNA.
DR RefSeq; XP_002116117.1; XM_002116081.1.
DR AlphaFoldDB; B3S768; -.
DR STRING; 10228.B3S768; -.
DR EnsemblMetazoa; TriadT60061; TriadP60061; TriadG60061.
DR GeneID; 6757245; -.
DR KEGG; tad:TRIADDRAFT_60061; -.
DR CTD; 6757245; -.
DR eggNOG; KOG2325; Eukaryota.
DR HOGENOM; CLU_557728_0_0_1; -.
DR InParanoid; B3S768; -.
DR OMA; MMLVYSY; -.
DR OrthoDB; 306020at2759; -.
DR PhylomeDB; B3S768; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF16; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..463
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 480 AA; 53160 MW; 9C1F733295890235 CRC64;
MKRWKVISTN VSIGVFFLLG GIEYAVIIPT LFNFVVNRFG GSNWMYGMIL SAFSFAQLFS
NPLMGYLCDR SKNAKWVVIF GNLFELGGNF LYFAAPSQYW LLGARLLCGF GAGAGSAILA
QIARTSTVAE RTKVFSLAMM ARQCGMLLGP AFNVFLKGLH FKIGPFQVDA FTSPGIFMAC
LFLLDELMIL FLYFDQPPLS KRERDGNQTS ESTEKSPIIK SGRMNNYGTG LDEESQHTDP
TVGINASCSI NASSDDEEIR IKKPKKKGFL VGILREELIV LLTAQFVVFF NQTSFETLVI
PLTEELLGWG ELANSIMYGV VGLLAIIVFL LITIISKKIE DRWLMVIGIV AQTFSLVWDI
GFFGQATRHT PTNLMAFIIS TFFIVSGVPF FIVSSSSLFS KLTDEETQGL TQGFRRAIAS
VATIFGPLYA GGLIHNLYAT FGVMAGLVVF LAIILFMSFK TLREPSKQRR KTAELNEDSQ
//
