ID B3SC19_TRIAD Unreviewed; 569 AA.
AC B3SC19;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0000259|PROSITE:PS50115};
GN ORFNames=TRIADDRAFT_64381 {ECO:0000313|EMBL:EDV19774.1};
OS Trichoplax adhaerens (Trichoplax reptans).
OC Eukaryota; Metazoa; Placozoa; Uniplacotomia; Trichoplacea; Trichoplacidae;
OC Trichoplax.
OX NCBI_TaxID=10228 {ECO:0000313|EMBL:EDV19774.1, ECO:0000313|Proteomes:UP000009022};
RN [1] {ECO:0000313|EMBL:EDV19774.1, ECO:0000313|Proteomes:UP000009022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Grell-BS-1999 {ECO:0000313|EMBL:EDV19774.1,
RC ECO:0000313|Proteomes:UP000009022};
RX PubMed=18719581; DOI=10.1038/nature07191;
RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U.,
RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L.,
RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J.,
RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., Dellaporta S.L.,
RA Rokhsar D.S.;
RT "The Trichoplax genome and the nature of placozoans.";
RL Nature 454:955-960(2008).
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DR EMBL; DS985267; EDV19774.1; -; Genomic_DNA.
DR RefSeq; XP_002117798.1; XM_002117762.1.
DR AlphaFoldDB; B3SC19; -.
DR STRING; 10228.B3SC19; -.
DR EnsemblMetazoa; TriadT64381; TriadP64381; TriadG64381.
DR GeneID; 6758966; -.
DR KEGG; tad:TRIADDRAFT_64381; -.
DR CTD; 6758966; -.
DR eggNOG; KOG0706; Eukaryota.
DR HOGENOM; CLU_023062_6_2_1; -.
DR InParanoid; B3SC19; -.
DR OMA; QEEWQSE; -.
DR OrthoDB; 389572at2759; -.
DR PhylomeDB; B3SC19; -.
DR Proteomes; UP000009022; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:GOC.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0048205; P:COPI coating of Golgi vesicle; IBA:GO_Central.
DR CDD; cd08831; ArfGap_ArfGap2_3_like; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR45686:SF4; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H; 1.
DR PANTHER; PTHR45686; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}; Reference proteome {ECO:0000313|Proteomes:UP000009022};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 13..119
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 221..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 62540 MW; 998A922C578CE28A CRC64;
MSDVPVATKA QIVAIFKKLS SIPSNKICFD CNSKNATWSS VTYGIFLCLD CSAIHRSLGV
HISFVRSTLL DQWNWLQLRQ MQVGGNANAR EFFQSHGLTV TDASAKYQSR VARMYREKLA
SLAAVTLKQY GTSTNITSPS PTTKEGDFFK DVSSVVSAPA AFPFLADAEE KKDFPRVTTD
HLSNRYQQPK REQPAVDTLK VNENPEPDTV KVATVRVDGV ESGTRKQAST IGKRKPITGK
KKGASSKQGL GARKITTDFS IVESAAAQDE EILRKERESG LVAEQELNDI ENRTPTRFVY
QEKKAGMTKL RETDPKKAEQ MERLGMAMGG RLPASAQSHS VAASMVEIDQ EDPAGSISTK
SKFANQPTSF DTDFFGNFES TQPSRYDSPF SDMNDWKSSR KSEKGYFEVD EREAAAAPSV
KSSAMSLSSR SRDISARYPK KDIFLKAETT RSTEHFHGAT AISSDDFFGS SGNKKSQVDA
PSIDLDQIKE GVSRVTNKLS NMASGVLGSL QCERRITSVS VAAKSEGKHI VIQNFVDVSH
QSIACISYFE TPFKLLPGIS NIIMPELNC
//
