ID B3SU92_SALSA Unreviewed; 232 AA.
AC B3SU92;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Homeobox protein HoxC6ba {ECO:0000313|EMBL:ABV82009.1, ECO:0000313|RefSeq:NP_001135139.1};
GN Name=HoxC6ba {ECO:0000313|EMBL:ABV82009.1};
GN Synonyms=hoxc6ba {ECO:0000313|RefSeq:NP_001135139.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:ABV82009.1};
RN [1] {ECO:0000313|EMBL:ABV82009.1, ECO:0000313|RefSeq:NP_001135139.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18424774; DOI=10.1093/molbev/msn097;
RA Mungpakdee S., Seo H.C., Angotzi A.R., Dong X., Akalin A., Chourrout D.;
RT "Differential evolution of the 13 Atlantic salmon Hox clusters.";
RL Mol. Biol. Evol. 25:1333-1343(2008).
RN [2] {ECO:0000313|RefSeq:NP_001135139.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC developmental regulatory system that provides cells with specific
CC positional identities on the anterior-posterior axis.
CC {ECO:0000256|ARBA:ARBA00003263}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the Antp homeobox family.
CC {ECO:0000256|ARBA:ARBA00009107}.
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DR EMBL; EF695273; ABV82009.1; -; mRNA.
DR EMBL; EU025716; ABW77537.1; -; Genomic_DNA.
DR RefSeq; NP_001135139.1; NM_001141667.1.
DR GeneID; 100196638; -.
DR KEGG; sasa:100196638; -.
DR CTD; 100196638; -.
DR OrthoDB; 728401at2759; -.
DR Proteomes; UP000087266; Chromosome ssa12.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001827; Homeobox_Antennapedia_CS.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR45659; HOMEOBOX PROTEIN HOX; 1.
DR PANTHER; PTHR45659:SF1; HOMEOBOX PROTEIN HOX-C6; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00032; ANTENNAPEDIA; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 139..199
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 141..200
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 88..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 218..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 26487 MW; E673E7EB25274023 CRC64;
MNSYFANPSL SCHLAGGQEV LPNVALNSAT YDAVRHYSSY GAAVAQNRIY SSPFYSPQDN
VVFGSSRGPY EYGSNVFYQD KDVLPSCRQS SLGQGAQTSL PQDYPSDQGR NGSQEQKGNI
QIFPWMQRMN SHSGVGYGSD RRRGRQIYSR YQTLELEKEF HFNRYLTRRR RIEIANALCL
TERQIKIWFQ NRRMKWKKES NLTSTLTESV SAGVSQDTGK EDTEEATEEK KE
//
