ID B3V7U2_TOBAC Unreviewed; 272 AA.
AC B3V7U2;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=NBS-coding resistance gene analog {ECO:0000313|EMBL:ACE79431.1};
DE Flags: Fragment;
GN Name=NBS173-3 {ECO:0000313|EMBL:ACE79431.1};
GN Synonyms=NBS173-4 {ECO:0000313|EMBL:ACE79450.1}, NBS173-5
GN {ECO:0000313|EMBL:ACE79460.1};
OS Nicotiana tabacum (Common tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=4097 {ECO:0000313|EMBL:ACE79431.1};
RN [1] {ECO:0000313|EMBL:ACE79431.1}
RP NUCLEOTIDE SEQUENCE.
RA Leng X., Xiao B., Wang S., Gui Y., Wang Y., Lu X., Xie J., Li Y., Fan L.;
RT "Identification of NBS-Type Resistance Gene Homologs in Tobacco Genome.";
RL Plant Mol. Biol. Rep. 28:152-161(2010).
CC -!- FUNCTION: Confers resistance to late blight (Phytophthora infestans)
CC races carrying the avirulence gene Avr1. Resistance proteins guard the
CC plant against pathogens that contain an appropriate avirulence protein
CC via an indirect interaction with this avirulence protein. That triggers
CC a defense system including the hypersensitive response, which restricts
CC the pathogen growth. {ECO:0000256|ARBA:ARBA00002074}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
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DR EMBL; EU713677; ACE79431.1; -; Genomic_DNA.
DR EMBL; EU713696; ACE79450.1; -; Genomic_DNA.
DR EMBL; EU713706; ACE79460.1; -; Genomic_DNA.
DR AlphaFoldDB; B3V7U2; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hypersensitive response {ECO:0000256|ARBA:ARBA00022667};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Plant defense {ECO:0000256|ARBA:ARBA00022667}.
FT DOMAIN 46..259
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACE79431.1"
FT NON_TER 272
FT /evidence="ECO:0000313|EMBL:ACE79431.1"
SQ SEQUENCE 272 AA; 30461 MW; 692E0FFC44B92DEE CRC64;
IIKHSPNNNL QAGNSSIGDS SSPRLHAPTH ENDMVGYNIE QANMLSQLTR DSPELEVISV
TGMGGIGKST FAKKLFSHPS VLSFFDIRGW VTVSEDYSYR NMLLGLLEDA NIGKEEDLDK
KSDSDLAVCL KQSLMGRRYL IVVDDIWSKN AWDEIRLCLP DDGKRSRVLL TTRDVEVAQY
ASSPKDPFRM HLLGPDDSWN LFYQKAFAEK GFPIEFEDVG KYIAKNCKGL PLMIAVVAKF
LSSKRTLEEW RKVAKSLSSL ADVDAYQQCS GE
//
