ID   B3XVV4_9EUKA            Unreviewed;       716 AA.
AC   B3XVV4;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   03-APR-2013, entry version 31.
DE   SubName: Full=Protein tyrosine kinase tec;
GN   Name=MoPTK-b;
OS   Monosiga ovata.
OC   Eukaryota; Choanoflagellida; Codonosigidae; Monosiga.
OX   NCBI_TaxID=81526;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=18267119; DOI=10.1016/j.febslet.2008.02.002;
RA   Suga H., Sasaki G., Kuma K., Nishiyori H., Hirose N., Su Z.H.,
RA   Iwabe N., Miyata T.;
RT   "Ancient divergence of animal protein tyrosine kinase genes
RT   demonstrated by a gene family tree including choanoflagellate genes.";
RL   FEBS Lett. 582:815-818(2008).
CC   -!- SIMILARITY: Contains 1 PH domain.
CC   -!- SIMILARITY: Contains 1 protein kinase domain.
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DR   EMBL; AB098166; BAG55489.1; -; mRNA.
DR   ProteinModelPortal; B3XVV4; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR   GO; GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR011993; PH_like_dom.
DR   InterPro; IPR001849; Pleckstrin_homology.
DR   InterPro; IPR000719; Prot_kinase_cat_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR011511; SH3_2.
DR   InterPro; IPR001452; SH3_domain.
DR   InterPro; IPR008266; Tyr_kinase_AS.
DR   InterPro; IPR020635; Tyr_kinase_cat_dom.
DR   InterPro; IPR001562; Znf_Btk_motif.
DR   Pfam; PF00779; BTK; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF07714; Pkinase_Tyr; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF07653; SH3_2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   PRINTS; PR00109; TYRKINASE.
DR   SMART; SM00107; BTK; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00252; SH2; 1.
DR   SMART; SM00326; SH3; 1.
DR   SMART; SM00219; TyrKc; 1.
DR   SUPFAM; SSF56112; Kinase_like; 1.
DR   SUPFAM; SSF50044; SH3; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
DR   PROSITE; PS50001; SH2; 1.
DR   PROSITE; PS50002; SH3; 1.
DR   PROSITE; PS51113; ZF_BTK; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Kinase; Nucleotide-binding; Transferase;
KW   Tyrosine-protein kinase.
SQ   SEQUENCE   716 AA;  79648 MW;  99616A46D4109990 CRC64;
     MDETIEREGI LQKRAQGFTK GGPKNWKTRF FRLTRTEFAY WEKDPRSSTD AKKKGSVPIS
     DVMAVEEXKD NTFDRTNLFQ VVYSCTTGPM VLYCQSPERN DRSAWVQALQ ALLLPAKRSK
     MFHPSYYDGK IWLCCKVESQ DSEGCQSVTP IIKASTAPTN AGMQFGGGPV QPMPTMVPGL
     SMPAPSMHGM PPPTGPKPSG RLSAPEAPPA ASLPPKPAAL LAAVMTGPGS PKAMRHAMEA
     PPMVTAPKPA ALLASMRGPS GASPTSPAPA SSPVAPAVVP ERKQVRVMFD YIATAAGDLT
     IHKDEMITIL EERPNWWKAQ NKHGEVGFVP SNYLCRIQGL EGEPWFRGRI SRAEAAAMLQ
     ITKQEGCFLV RESETQPGEY TLSLSHNEGV RHYRIQHIEG QYFVNENHRF DSIPQLIEYH
     KLNGGGIVTR LRRAINDANA PISVGLGHDM WELSRDEFEL GRELGSGQFG IVQQARYRNG
     QAVAIKMMKE GKMSADDFIS EAVVMRDLSH PHLVQLLGVC TKGGPLWIIT ELMSKGCLLN
     YLRDHKELRG EPQILHMMCV HIASAMEYLE SKGFIHRDLA ARNCLLGDNY VVKVADFGLA
     RFVTDNEYIS SEGAQFPIKW SAPEVINFSR FSTKSDVWSF GVTVWEIWSF GTIPYPAHRN
     HEISGLLQSG YRMQCPEGAP MQAYQLILAC WHQDPEFRPT FAEISVRLRD NKEEYG
//