ID B4DHG7_HUMAN Unreviewed; 320 AA.
AC B4DHG7;
DT 23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 23-SEP-2008, sequence version 1.
DT 03-MAY-2023, entry version 66.
DE SubName: Full=cDNA FLJ55310, highly similar to Guanine nucleotide-binding protein G(olf) subunit alpha {ECO:0000313|EMBL:BAG58129.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG58129.1};
RN [1] {ECO:0000313|EMBL:BAG58129.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Brain {ECO:0000313|EMBL:BAG58129.1};
RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA Sugano S., Nomura N., Isogai T.;
RT "NEDO human cDNA sequencing project focused on splicing variants.";
RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the G-alpha family. G(s) subfamily.
CC {ECO:0000256|ARBA:ARBA00007172}.
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DR EMBL; AK295088; BAG58129.1; -; mRNA.
DR AlphaFoldDB; B4DHG7; -.
DR PeptideAtlas; B4DHG7; -.
DR GO; GO:0016020; C:membrane; IEA:UniProt.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000367; Gprotein_alpha_S.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF233; GUANINE NUCLEOTIDE-BINDING PROTEIN G(OLF) SUBUNIT ALPHA; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00443; GPROTEINAS.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 2: Evidence at transcript level;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 320 AA; 37556 MW; D69EE9910C7D7AD9 CRC64;
MRILHVNGFN PEEKEQKILD IRKNVKDAIV TIVSAMSTII PPVPLANPEN QFRSDYIKSI
APITDFEYSQ EFFDHVKKLW DDEGVKACFE RSNEYQLIDC AQYFLERIDS VSLVDYTPTD
QDLLRCRVLT SGIFETRFQV DKVNFHMFDV GGQRDERRKW IQCFNDVTAI IYVAACSSYN
MVIREDNNTN RLRESLDLFE SIWNNRWLRT ISIILFLNKQ DMLAEKVLAG KSKIEDYFPE
YANYTVPEDA TPDAGEDPKV TRAKFFIRDL FLRISTATGD GKHYCYPHFT CAVDTENIRR
VFNDCRDIIQ RMHLKQYELL
//
